Prediabetes

This might be a reason not to use a DPP-4 for those with long standing diabetes… Reduction in the glucose-regulating hormone glucagon-like peptide-1 (GLP-1) appears to occur before the development of type 2 diabetes and obesity, according to new published research. Investigator Kristine Færch, PhD, senior research fellow at the …

Dental visits may allow for diabetes screening and monitoring glucose control in at-risk patients… A new study suggests that using gingival crevicular blood, collected during dental visits, for HbA1c testing produced values that were nearly identical to those obtained using finger stick blood. Correlation was 0.991 between the HbA1c values …

In this longitudinal population-based study, 1609 patients were followed between 2002 and 2014 (mean, 10.9 years) to determine whether prediabetes affected risk for cardiovascular disease (CVD) or diabetes mellitus (DM)… No association was found between prediabetes and the development of cardiovascular disease using models that were adjusted for several factors …

Corneal confocal microscopy (CCM) can predict incipient peripheral neuropathy in patients with type 1 diabetes… The technique involves the examination of unmyelinated nerve fibers at high magnification using a laser-scanning corneal confocal microscope to image the subbasal nerve plexus of the patient’s cornea. Increased severity of diabetic peripheral neuropathy is …

For every 0.56 mmol/L increase in fasting blood glucose there was a 14% increase in the rate of pancreatic cancer… In previous studies, an assumption has been made that diabetes may be either a risk factor or a symptom of pancreatic cancer. To investigate this connection, researchers examined both linear …

Steve Freed: Please tell us a little about yourself and this new compound, BTI320. Dr. David Platt: My area of expertise is the recognition between carbohydrate and protein. In my previous two companies, I developed drugs for a recognition between sugar and protein. In one case, it was a protein that …

Steve Freed: Let’s start out with a little background about Qsymia and Belviq. What is the FDA allowing you to treat with the drugs? Dr. Timothy Garvey: In 2012, the FDA approved two new weight loss medications. In 2014, another medication was approved. That is three new medications. We hope …

Using a computer model to analyze data from the 2003-2010 NHANE survey, researchers found that significant cost savings could be made if prediabetes patients made lifestyle changes… The Community Preventive Services Task Force recommends combined diet and physical activity promotion programs for people at increased risk of type 2 diabetes, …

Serum levels of 2 microRNAs, miR-192 and miR-193b, can be used to identify individuals with prediabetes, researchers report… The uncontrolled hyperglycemic excursions associated with prediabetes are stressful for the body, and miRNAs are thought to be critical regulators of stress. Dr. Marcelina Párrizas from Diabetes and Obesity Research Laboratory, Barcelona, …

A new set of "guiding principles" for the care of people with diabetes and those who are at risk for it has been issued from the NDEP with the endorsement from several medical societies…