Conditions

Testing for monogenic diabetes involves providing a blood sample from which DNA is isolated. The DNA is analyzed for changes in the genes that cause monogenic diabetes. Abnormal results can determine the gene responsible for diabetes in a particular individual or show…

MODY is a monogenic form of diabetes that usually first occurs during adolescence or early adulthood. However, MODY sometimes remains undiagnosed until later in life. A number of different gene mutations have been shown to cause MODY, all of which limit the ability of…

NDM is a monogenic form of diabetes that occurs in the first 6 months of life. It is a rare condition occurring in only one in 100,000 to 500,000 live births. Infants with NDM do not produce enough insulin, leading to an increase in blood glucose. NDM can be mistaken …

The most common forms of diabetes, Type 1 and Type 2, are polygenic, meaning the risk of developing these forms of diabetes is related to multiple genes. But some rare forms of diabetes result from mutations in a single gene and are called monogenic….

Researchers are studying the genetic causes of and metabolic processes related to diabetes. Discoveries about monogenic forms of diabetes may contribute to the search for the causes of and treatments for Type 1 and Type 2 diabetes. For information about clinical trials related to diabetes and genetics…

Lilly Jaffe, of Chicago, was diagnosed with type 1 diabetes more than ten years ago, at the tender age of one month. What has happened to Lilly over the past few years is remarkable….

Researchers have found that a gene associated with the onset of Type 2 diabetes also is found at lower-than-normal levels in people with Alzheimer’s disease….

Insulin-Pump Therapy + New Types of Insulin Preparations + Complications of Insulin Therapy, Chapter 9 – Part 6 Steve V. Edelman, MD Robert R. Henry, MD Insulin-Pump Therapy Insulin-pump therapy has been traditionally used for people with Type 1 diabetes. People with Type 1 diabetes usually do not have insulin …

A research team has identified the mechanism behind a single gene linked to the causes of both Alzheimer’s disease and Type 2 diabetes. A gene for a protein called SorCS1, which can cause Type 2 diabetes, impacts the accumulation of amyloid-beta (Abeta) in the brain. Abeta plays a key role …

Insulin Therapy, Chapter 9 – Part 1 Steve V. Edelman, MD, Professor of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego Robert R. Henry, MD, Professor of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego   Insulin therapy most commonly is reserved for patients …