Alzheimer’s

Insulin resistance associated with a lower regional cerebral glucose metabolism, worsened memory performance… A recent study published in JAMA on July 27th evaluated 150 cognitively normal male and female adults with an average age of nearly 61 years old. Data collected from the patients included cognitive testing, fasting blood glucose …

What do alcohol consumption, smoking, obesity, and diabetes have in common… Previous studies have shown that cardiovascular risk factors are linked to cognitive decline leading to Alzheimer’s disease and dementia. However, we don’t currently have effective treatments for Alzheimer’s disease, so the focus is on prevention. Being able to understand …

Elevated blood glucose caused increase in amyloid beta leveles in the brain… While many earlier studies have pointed to diabetes as a possible contributor to Alzheimer’s, the new study – in mice – shows that elevated glucose in the blood can rapidly increase levels of amyloid beta, a key component …

Study conducted in mice has shown that sitagliptin might offer beneficial effects in reversing cognitive impairment… Alzheimer’s disease (AD) is the most common form of dementia. Symptoms progress slowly and worsen over time resulting in interference with common daily activity. There is no known cure of AD, but the use …

Older veterans with T2DM and dementia may need to decrease intensity of diabetes medications… One study predicts that the prevalence of diabetes among adults aged ≥65 years is projected to increase dramatically by 2050. Other studies have observed that dementia affects up to 16% of diabetic patients aged ≥65 years …

But the association with between hypertension, diabetes, and dementia is not clear…. Previous studies have found a correlation between individuals with hypertension and diabetes, and the subsequent development of dementia. The purpose of this cross-sectional study was to analyze the effect of diabetes and hypertension on cognitive scores conducted on …

Structured intervention led by Community Health Workers shows success…. Noticeable discrepancies exist among Latinos American in socioeconomic status, health insurance coverage, and use and quality of healthcare services. Obesity and physical inactivity which is associated with poor diabetes control are more prevalent among this population. A recent study has been …

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Particular groups of patients with diabetes are at risk of different psychological problems (Table 25.1). Many chil­dren show remarkable resilience to the diagnosis of diabetes, but about one-third have some temporary psychological distress, mostly ‘adjustment disorders’ such as difficulty in sleeping, depression, …

Participants performed significantly worse on the working memory tasks…. Type 2 diabetes can be associated with cognitive impairment and the risk of Alzheimer’s disease. No studies have yet shown how type 2 diabetes affects working memory task and is related to brain function. The study used participants from the Beijing …

Can pioglitazone reduce more than blood glucose levels?…