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Cannabis-Based Medicine

Feb 23, 2019

A recent Cochrane Review found which one of the following to be true about the effects of cannabis-based medicines on neuropathic pain?



Correct Answer: a) All cannabis-based medicines (herbal, plant-derived, synthetic) pooled together were more effective than placebo for pain relief.

Explanation: The review found a low to moderate level of evidence that cannabis-based medicines outperformed placebo for pain relief, reduction of pain intensity, improved sleep, and psychological distress. However, herbal cannabis was comparable to placebo for moderate pain relief. Although there was insufficient evidence of increased serious adverse events in those who received cannabis-based medicines vs placebo, more people receiving cannabis-based medicines left the study because of adverse effects.

References:  Mücke M, et al. Cochrane Database Syst Rev. 2018;3:CD012182.