Nitric Oxide Synthase (NOS) is the enzyme that generates NO from L-arginine as described in Part 1 of this series. However, the enzyme exists in three different forms called isoforms. Each isoform synthesizes NO but does so under different conditions. Often all three isoforms will be found in the same …

This is the first in a series of articles that relate specifically to nitric oxide (NO), a free radical gas that is a powerful regulator of circulation (It is an endogenous vasodilator.) and a neurotransmitter (It helps in the processing of nerve signals as they cross synapses.). L-arginine, one of …