A new finding from the SCALE trial.

Gastric bypass surgery may treat type 2 diabetes in selected patients.

Changes in serum metabolomic profile affect eGFR in patients with type 1 diabetes.

Genetic predisposition to a higher waist-to-hip ratio may lead to diabetes.

Proponents may suggest an advantage of one over the other, but the data is not so clear.

The diabetes drug empagliflozin reduces all of the following CV risk factors except: a. Blood pressure b. Visceral adiposity c. Low-density lipoprotein cholesterol d. Triglycerides e. Atrial stiffness Follow the link to see if you got it right!

Should physicians be able to help patients end their lives? Follow the link to share your opinion and see what your colleagues say.

Woman, 57 years of age, prediabetes, hyperlipidemia, class I obesity and history of gestational diabetes. I’ve been working with her for the past two years. The first year she was very motivated because of her new diagnosis of prediabetes and her weight being what it was. Her son was getting married and she wanted to lose weight for the wedding. We discussed a plan for her.

In this week's Homerun Slides, the results of the HOPE trial and the assessment of albuminuria to predict cardiovascular risk.

Regulation of glycogenolysis: Glycogen metabolism is regulated by reciprocal changes in the activities of glycogen synthase and glycogen phosphorylase. Net glucose production from glycogen occurs when phosphorylase activity is higher than synthase activity. Activation of glycogen phosphorylase is the culmination of a “glycogenolytic cascade” that is initiated by the binding of glucagon or beta-adrenergic agonists to their receptors in liver cells.