The FDA first rejected the drug combination in February 2011, asking the company to conduct a cardiovascular-outcomes trial because of concerns about the CV safety profile of bupropion/naltrexone when used long-term in a population of overweight and obese subjects…. 

Methazolamide, proven in a study to be beneficial in diabetes treatment, could be the archetype for a new class of agents used to treat type 2 diabetes and related conditions…. 

But results from the longitudinal study also confirmed that improvements in insulin sensitivity were unaltered by weight regain following Roux-en-Y gastric bypass…. 

Sleeve gastrectomy is now a treatment option for patients with obesity to help reduce weight and manage diabetes….

Diabetic women who use sulfonylureas for a long time could have a higher risk of developing CHD…. 

Metformin seems to have positive effects on body composition, insulin sensitivity, and glucose homeostasis in patients recently diagnosed with type 2 diabetes…. 

Slow caffeine metabolizers who drink more than three cups a day have the highest risk…. 

Daughters exposed to maternal hyperglycemia will have a higher risk of childhood adiposity…. 

About one in every 1,000 individuals carries a variant in PPARG, which is treatable with tailored pharmacotherapy…. 

This month’s edition of the Insulin Practice series is full of great information about new insulins that we will be able to use in the near future. These products will make it easier for all of us to develop better treatment plans for our patients, and mixing the old with …