In this week’s Homerun Slides, we cover the importance of the Incretin Effect with an examination of the mechanisms of action of GLP-1 agonist and DPP-4 inhibitor drugs including the cardioprotective aspects of these medications…. To download these slides in PowerPoint (.ppt) format, use this link: Diabetes Mellitus 101 for Cardiologists, Part 11 …
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Handbook of Diabetes, 4th Ed., Excerpt #23: Skin and Connective Disorders in Diabetes
Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Diabetes affects the cellular biochemistry of skin and connective tissues, in particular collagen synthesis and structure, as well as cutaneous microvascular blood flow. Several non-infective skin conditions are associated with type 1 and/ or type 2 diabetes (Box 24.1). Diabetic dermopathy (‘shin …
Read More »Editor’s Note, The Best of 2014
We all know that when it comes to healthcare, "analytics" is a word that has jumped to the forefront. Hospitals, prescribers, and insurance companies all can earn more money if their analytics are good, and can be penalized if the results head downward. This same concept comes into play on …
Read More »Lilly to Partner with Adocia in Developing BioChaperone Insulin Lispro
Eli Lilly has announced they are partnering with Adocia in a worldwide licensing collaboration focused on developing an ultra-rapid insulin, known as BioChaperone Lispro, which is currently in Phase Ib studies.
Read More »Adverse Outcomes Up with High A1c in Late Pregnancy for Type 1 Women
An HbA1c of 6.5-6.9% at 26 weeks’ gestation correlated with significantly elevated risk of preterm delivery, preeclampsia, need for neonatal glucose infusion, and a composite adverse outcome… Michael J.A. Maresh, M.D., from St. Mary’s Hospital in Manchester, U.K., and colleagues conducted a prospective assessment involving 725 women with type 1 …
Read More »Misconceptions about the Chemistry of Weight Loss
When people lose weight, where does it actually go? Two Australian researchers found that most people don’t know….
Read More »Statin Therapy Does Not Reduce Risk of Fracture
In an analysis of data from the JUPITER trial, higher baseline hs-CRP level was also not associated with an increased risk of incident fracture…
Read More »Simple Breath Test May Aid Early Diagnosis in Children
Increased breath acetone was linked to increases in beta hydroxybutyrate (a ketone) levels in the blood… Researchers may have identified a chemical marker for type 1 diabetes in the breath of children. Around 1 in 4 children with type 1 diabetes are unaware they have a condition until they develop …
Read More »Are There Good and Bad Carbs for Patients with Diabetes?
New research suggests that for non-diabetic people who follow a healthful diet, the glycemic index may not be very important…
Read More »Five Major Concerns for Physicians and Patients in 2015
Boston-based Physicians Foundation released its 2014 Watch List of five issues projected to impact physicians and patients next year, based on its Biennial Physician Survey…
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