Rofecoxib significantly increased systolic blood pressure, while celecoxib (Celebrex) and naproxen did not.

Despite differences in pathophysiology and metabolism, patients with type 1 and type 2 diabetes do not differ with respect to coronary vasodilator function.

If the combination is used, repaglinide dosage should be greatly reduced and blood glucose concentrations carefully monitored. Gemfibrozil raised the plasma concentration of repaglinide by 5.5-15.0 times and prolonged its half-life from 1.3 to 3.7 hours.

European drug regulators warned on Wednesday that Novo Nordisk’s oral antidiabetic Prandin/NovoNorm (repaglinide) can cause severe hypoglycemia if patients take the lipid-lowering agent gemfibrozil at the same time.

The world’s first embryonic stem cell bank opened in Britain on Wednesday, breaking new ground in one of the most controversial areas of medical research.

There appears to be no direct connection between thiazolidinedione-related fluid retention and cardiac dysfunction in diabetic patients with chronic heart failure.

Cholesterol controlling drug Simvastatin fighst insulin resistance Over the past decade, evidence has accumulated indicating that nitric oxide (NO) may play a key role in the control of metabolic and cardiovascular homeostasis, as evidenced by mice lacking the gene for endothelial nitric oxide synthase (eNOS) that are insulin resistant and …

A history of irregular menses is an independent predictor of gestational diabetes mellitus.

Diabetic women and patients with insulin-dependent diabetes mellitus (IDDM) are at greater risk of cardiac death than other diabetic patients.

Metformin prevented diabetes a substantial 25% after withdrawal. The benefits of metformin in preventing diabetes appear to persist in some patients after the drug has been discontinued, according to a report in the April issue of Diabetes Care.