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Diabetes In Control

Issue 175 Item 4 A New Interaction Between Gemfibrozil and Avandia

Many times these drugs are combined so patients will get gemfibrozil (Lopid, etc) to lower triglycerides and increase HDL. But gemfibrozil inhibits the CYP450 enzyme that metabolizes Avandia which will boost Avandia levels which, increases Avandia’s glucose lowering effects. This can lead to hypoglycemia in patients who use Avandia along …

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