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Amino Acids Predictive of Diabetes and CVD

Jul 19, 2013

The amino acids tyrosine, isoleucine, and phenylalanine show a strong predictive nature for….

Recently, there has been a diabetes epidemic that has led to an increase of cardiovascular disease. If we are able to examine these amino acids more closely then we may be able to prevent diabetes and also the development of complications associated with diabetes such as cardiovascular disease.


A matched case control study was conducted to evaluate the predictive relationship between these amino acids and diabetes and its complications. The population for this study was taken from the Malmo Diet and Cancer Cardiovascular Cohort. None of the participants had any signs of cardiovascular diseae. During the 1 year of follow up, 253 of these participants developed cardiovascular disease. The three amino acids associated with diabetes were profiled in baseline plasma samples.

Ultimately, the study found that these branched chained amino acids were also predictive for cardiovascular disease development and showed an early link between diabetes and cardiovascular disease vulnerability.

Magnusson Martin, Lewis Gregory et al. 2012 November 15. AEur Heart J (2013) 34 (26): 1982-1989.