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In new-onset type 1 diabetes, hybrid closed-loop control (HCLC) followed by sensor-augmented pump (SAP) therapy did not provide benefit in preserving beta-cell function compared with current standards of care. Diabetes Care Oct 2013 

Data presented at the American Society for Bone and Mineral Research meeting showed older women with type 2 diabetes had lower trabecular bone score and 25-hydroxyvitamin D levels and higher bone alkaline phosphatase levels compared with controls. "We found that the trabecular bone score was worse in the patients with …

MannKind again filed an application with the FDA for approval to market its Afrezza inhalation powder, a fast mealtime insulin treatment intended to improve glycemic control for diabetes patients. The application was based on data from two late-stage trials. Mannkind Press Release Oct 2013 

Analysis in the Annals of Internal Medicine revealed undergoing comprehensive lifestyle interventions may help stem the odds of type 2 diabetes in high-risk patients. However, lifestyle initiatives did not appear to cut the risk of all-cause mortality in those who had diabetes, researchers noted. Annals of Internal Medicine, Oct 15, …

There should be little difference between the lifestyle advice given to diabetics and that given to the general public, results of a large, prospective study suggested. Although diabetics in the study had a 62% higher risk of dying than people without a diabetes diagnosis, diabetes status did not substantially influence …

Recently developed ultrasensitive assays capable of detecting C-peptide under 5 pmol/l now allow very low levels of C-peptide to be detected in patients with long-standing type 1 diabetes. Most patients with long-duration type 1 diabetes continue to secrete very low levels of endogenous insulin, which increase after meals. This is consistent …

Scientists Discover Compound That Arrests Neurodegeneration See this week’s Item #10.

The three winners of this year’s Nobel Prize in physiology or medicine discovered mechanisms for how hormones, enzymes and other materials are transported inside cells and used throughout the body, helping to reveal the operations of diabetes and other diseases. The three are James E. Rothman of Yale University, Randy …

Dutch researchers found nonmetastatic breast cancer patients who had diabetes were 23% less likely than those without diabetes to suffer cancer recurrence, and those in the oldest age group had a 33% reduced risk of relapse. However, patients with or without diabetes but who had other comorbidities showed worse overall …

Thirty-six percent of Americans indulged in dessert at least twice a week in 2010 but now the number is over 40% according to a new report. The report also revealed that more Americans are eating desserts during morning and afternoon hours as snacks or post-meal treats. "Consumers aren’t holding off …