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Did You Know

Obama Proposes Third Year of Medicaid-Medicare Pay Parity

The White House wants to add 1 more year to a provision of the Affordable Care Act that raises Medicaid reimbursement to Medicare levels for evaluation and management services, and for vaccination administration performed by primary care physicians. The act authorized this parity in Medicaid-Medicare pay for 2013 and 2014 …

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SGLT-2 Inhibitor Gets Turned Down by the FDA

Quality issues in the manufacturing plant prevents FDA from final approval. The investigational type 2 diabetes drug empagliflozin won’t win the FDA’s approval until "previously observed deficiencies" at a manufacturing plant are fixed. Eli Lilly and its partner, Boehringer Ingelheim, said the FDA had issued a complete response letter in …

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New Type 1 Diabetes Treatment Passes First Test

A clinical study on a T1D treatment developed by Dr. Eli Lewis, a BGU researcher, in collaboration with the University of Colorado Health Science Center, had an "exceptional outcome" after an eight week treatment of the anti-inflammatory serum protein, Alpha1-Antitrypsin (AAT). "Following treatment of eight to 12 weeks with AAT, …

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Can Exercise Alter Metabolism Gene Expression Patterns?

Researchers found that short-term overeating and reduced physical activity lowered participants’ insulin sensitivity and altered expression patterns of several genes and proteins within adipose tissue. The study included 26 healthy, habitually active men aged 18 to 32 years. The affected genes are involved in nutritional homeostasis, metabolism, and insulin action …

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Night Shift Workers More Likely to Have “Pro-Inflammatory” Diet

Michael Wirth, MSPH, Ph.D., of the University of South Carolina, Columbia, analyzed the relationship between shiftwork and pro-inflammatory diet using data from a nationwide sample of employed adults. Based on diet questionnaires, the researchers calculated a "dietary inflammatory index" (DII) for each individual. The greater the DII score, the more …

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Oral Insulin Capsules for Type 1

Oramed has submitted a protocol to the FDA to initiate a Phase 2a trial of its orally ingestible insulin capsule, ORMD 0801, for type 1 diabetes. The double-blind, randomized, placebo controlled, seven-day study design will be carried out at an inpatient setting on twenty-four type 1 diabetic patients. It’s hope …

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180 Diabetes Drugs in Development

America’s biopharmaceutical research companies currently are developing 180 new medicines to help the nearly 400 million people who have diabetes worldwide. These medicines in development — all either in clinical trials or under review by the FDA — include 30 for type 1 diabetes, 100 for type 2 and 52 …

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New Evidence for Obesity Risk in the Early Years

When researchers at Emory’s Rollins School of Public Health followed 7,738 kids over the course of nine years they found that kindergarteners who were overweight had four times the risk of becoming obese by the age of 14 years as normal-weight kindergartners. More than 45% of the obesity cases that …

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Texting-based Diabetes Program Cuts Costs, Improves Outcomes

Diabetes patients who participated in a text message initiative attained significant reductions in A1c, greater satisfaction, and fewer visits to nondiabetes specialists at six months compared with a control group, a study indicated. Patients in the treatment arm also had lower medical expenses during the same period than the controls. …

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