Researchers found that short-term overeating and reduced physical activity lowered participants’ insulin sensitivity and altered expression patterns of several genes and proteins within adipose tissue. The study included 26 healthy, habitually active men aged 18 to 32 years. The affected genes are involved in nutritional homeostasis, metabolism, and insulin action processes. Daily vigorous exercise decreased and in some cases, prevented these changes. Walhin JP. J Physiol. 2013; doi: 10.1113/jphysiol.2013.26270
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