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ADA 81st Symposium: Cardiovascular and Kidney Outcomes in Efpeglenatide

Jul 24, 2021
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Alan Martinez, PharmD Candidate, University of South Florida Taneja College of Pharmacy

With the introduction of this glucagon-like peptide-1 receptor agonist (GLP-1 RA), efpeglenatide, could we see new cardiovascular and renal benefits for patients with type 2 diabetes? 

Patients with type 2 diabetes are at a higher risk of developing other complications if their HbA1c and glucose levels remain above goal. In addition, common comorbidities accompanying diabetes are cardiovascular and renal-based; this makes GLP-1 RAs a great option as they have shown to improve these outcomes in this patient population. Efpeglenatide is an exendin-4 (animal) based GLP-1 RA with a long half-life, thus administered subcutaneously once weekly. The purpose of the study is to assess the effectiveness of efpeglenatide in patients with type 2 diabetes concerning cardiovascular and kidney outcomes....


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