Diabetes In Control. A free weekly diabetes newsletter for Medical Professionals. News and information for Medical Professionals.
TOP STORIES — Diabetes News and Research
How to Address Those Nagging Joint Injuries and Pain
By Sheri Colberg, PhD
Letter from the Editor
As we grow older our bodies like to remind us that we are not the youngsters we used to be. Aches and pains become more frequent, and we can’t seem to do all the activities we did in the past. This is often exacerbated if we have diabetes.
Our first solution is to try to move and stretch more; however, most of us and our patients do not have the expertise to select the proper techniques for loosening and strengthening our muscles.
This week our exercise guru, Dr. Sheri Colberg, takes you through her own journey of treating the aches and pains, and the new discoveries she made along the way.
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We can make a difference!
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Dave Joffe
Editor-in-chief
TOP STORIES — Diabetes News and Research
By Sheri Colberg, PhD
In late 2017, one of my columns addressed whether you can determine if your joint issues are related to being active, normal aging, or diabetes. The answer was that you really couldn’t determine the exact cause(s), but any or all of them may be contributors. Does it matter more if you know the underlying cause if you can figure out the best treatment?
A new analysis of the D2d study suggests higher serum vitamin D levels may be necessary to reduce diabetes risk.
Metformin is often associated with lactic acidosis, especially in patients with kidney disease. A recently published study questions this association in patients with mild to moderate disease.
Did You Know? Lettuce Lowers Postprandial Blood Glucose:
Intake of various types of lettuce, like red oak, butterhead, and cos, could help prevent increases in blood glucose and cholesterol levels, according to a study published in the journal Recent Patents on Food, Nutrition & Agriculture. According to recent research, natural dietary fiber from salad vegetables can reduce glucose and lipid absorption and breakdown rates, thus preventing increases in postprandial blood sugar and cholesterol levels.
Prevention of spikes in blood sugar right after eating a meal is an important therapeutic target. It helps optimize blood sugar control and mitigates damage to our arteries, thereby decreasing the long-term risk of severe complications like heart attacks and strokes.
For the study, fiber was prepared from each type of lettuce using an enzymatic method and then characterized. Physical properties, including solubility and water-binding, swelling, cation-exchange, and oil-binding capacities, and antihyperglycemic and antihypercholesterolemic effects of fiber, were investigated. The results showed that:
a. The hydration capacity of total dietary fiber and insoluble fiber from most sources was significantly different from cellulose.
b. Adsorption and diffusion of glucose were directly proportional to incubation time, and the diffusion rate was considerably lower in the treatments containing fiber than the cellulose control.
c. Fiber from these vegetables also inhibited amylase and alpha-glucosidase activities.
d. Moreover, fiber from all sources exhibited significantly higher sodium cholate and cholesterol-binding capacity than cellulose and retarded pancreatic cholesterol esterase activity in a concentration-dependent manner.
Therefore, the authors concluded that “natural dietary fiber from salad vegetables can reduce glucose and lipid absorption and breakdown rates, thus preventing increases in postprandial blood sugar and cholesterol levels, which can be beneficial to human health.”
Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:
Alexandria Bartley, PharmD. Candidate, Florida Agricultural & Mechanical University, College of Pharmacy and Pharmaceutical Sciences
Louise Brown, PharmD Candidate, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences
Aleksandra Kusic, PharmD Candidate, Florida A&M University, College of Pharmacy and Pharmaceutical Sciences
A’Kira Shavers, PharmD Candidate, South College School of Pharmacy
Jonnessia Winslow, PharmD Candidate, South College School of Pharmacy
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