July 11, 2017 : DCMS #353

DISASTERS AVERTED — Near Miss Case Studies

Stephen Clancy – Taking Diabetes to the Professional Level

EXCLUSIVE INTERVIEW — Candid Video Interviews with Top Practitioners

Dr. Jaime Davidson on New Drugs and Their Impact on Patient Health

View Video | Read Transcript

HOMERUN SLIDES — Great Clinical Presentation Highlights

A Unifying Pathophysiologic Approach to The Complications of Diabetes in the Context of the Beta-cell Classification of Diabetes Part 2

CLINICAL GEMS — The Best from Diabetes Texts

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #81: Insulin actions in vivo: glucose metabolism Part 8 of 9

MOST POPULAR ARTICLES OF THE MONTH

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Many times we hear our patients complain that they are limited because of their diabetes, and they then start to regress, blaming the disease for everything. Would that be worse if you were a top athlete just coming into your prime? And what if your medical team told you that the sport you had chosen to excel in was too dangerous to participate in if you had diabetes?

This week, as the Tour de France moves into its second week, we have the story of Stephen Clancy, who was Ireland’s top young cyclist in 2012, diagnosed with diabetes in the next year, and worked his way up to participating in the upcoming Tour of Utah race with some of the same participants riding in France today. His story goes to show that no one should be allowed to use diabetes as an excuse.

Dave Joffe

Editor-in-chief

In his fifth year with Team Novo Nordisk, Stephen Clancy is slated to race his second consecutive Tour of Utah. At last year’s race, Stephen said it was an unforgettable experience racing at arguably the toughest race in the United States.

In this Exclusive Interview, Dr. Davidson discusses his thoughts on new drugs and their impact on patient health, such as DKA.

In this week’s Homerun Slides, the phenotypic presentation of the beta-cell.

Glucose phosphorylation and glucose transport are tightly coupled phenomena. Isoenzymes of HK (HK-I to HK-IV) catalyze the first committed intracellular step of glucose metabolism, the conversion of glucose to G-6-P. HK-I, HK-II, HK-III are single-chain peptides that have a number of properties in common, including a very high affinity for glucose and product inhibition by G-6-P.

Ralph DeFronzo and his researchers at UT Health at San Antonio announced that they have cured type 1 diabetes.

As we know, the most ineffective medication is the one needed but never taken. There are many reasons our patients don’t take prescription medicines, but a biggy is the cost. If a medicine is too expensive, the patient will not fill the prescription, therefore won’t take it. For example, when ordering an SGLT-2 and/or GLP-1, each can cost hundreds or more for a month’s prescription. Some are covered for both. Some are covered for one brand, but not the other.

Study shows age-related comorbidities decreased in males over 65 who take metformin.