Cardiovascular Risk Higher for Women Than Men With Type 2 Diabetes

Women with type 2 diabetes face a higher risk of cardiovascular disease than do men with type 2 diabetes

https://www.diabetesincontrol.com/modules.php?name=News&file=article&sid=4052

Dr. Adrienne A.M. Zandbergen and colleagues from Erasmus University Medical Centre, Rotterdam, the Netherlands investigated whether female sex was associated with cardiovascular disease, cerebrovascular disease, peripheral artery disease, and death, independently of recognized cardiovascular risk factors related to type 2 diabetes.

The study followed 46 men and 21 women with diabetes. They were normotensive but had microalbuminuria. During a mean follow-up of just under 5 years, eight women (38.1%) and six men (13.4%) met the end point.

Women were 3.19 times more likely than men to develop cardiovascular disease, the investigators calculate. After adjustment for age, blood pressure, body-mass index, dyslipidemia, smoking, and urinary albumin excretion, the risk increased to 6.4-fold, and adjustment that included retinopathy increased the risk to 8.23-fold.

"We conclude that female sex is an independent risk factor for macrovascular disease and death in our study population of normotensive patients with type 2 diabetes and microalbuminuria," the researchers say.

"Further research is needed to fully elucidate the pathogenesis of this excessive risk in women with type 2 diabetes because, at this point, we did not find risk indicators that discriminate between women with high and low risk of cardiovascular disease," Dr. Zandbergen and colleagues comment.

Diabetes Care 2006;29:1851-1855
===========================

Advertisement
Do you have patients in pain? Over 4,800 Anodyne Therapy Care Providers are increasing circulation and reducing pain for thousands of patients per month. To find out how you can help your patients get back to life, click here.
https://www.diabetesincontrol.com/annodyne/anodyne10_31_01.php