January 2, 2016 : Issue #814

• Warfarin with Sulfonylurea Increases Risk of Hypoglycemia Events
• Study Shows Liraglutide Helps To Reduce Sleepiness
• Liraglutide Success Shown Dependent on Early Weight Loss
• Diabetes Linked to Increased Risk of Tooth Loss
• Dapagliflozin Significantly Improves Blood Pressure
• Antioxidants May Help Reduce Diabetes Risk

Happy New Year!

Now that the last leftovers of the holidays are gone and the last big party of the season is over, our patients will make resolutions to eat better, lose weight, exercise more and lower their A1c’s. There will be at least 100 new commercials, YouTube videos, and gadgets ready for our patients to spend their money on. This also means that patients will be coming to you for help. Now would be a good time to consider using the GLP-1 analogs. This week we have 2 articles that will help you understand how this class of drugs can be of great benefit for weight loss, and even in giving patients the energy to exercise more (see Item 2 and  Item 3).

You might also consider an SGLT-2 inhibitor for these patients. Item 6 shows how they can affect blood pressure as well as glucose levels. To gain even more knowledge, you will want to read our special newsletter on SGLT-2 inhibitors that we sent out earlier this week.

Announcements:

Free CME Courses
Our web site CME resource is back online! Be sure to check out the new CME courses posted there. Courses are currently available on topics including: Advances in the Medical & Surgical Management of Obesity; Diabetic Retinopathy; Strategies to Improve Prevention and Treatment of Diabetes; and more!

dLifeTV.com: Sunday, January 3, 7PM ET

From dLife.com: “Jim Turner asks real people living with diabetes if their spouse helps or hinders their diabetes health; Chef Michel Nischan shares his recipe for a flavorful chicken ranch salad; Jim Turner asks real people living with diabetes the most insensitive thing someone without diabetes has said to them; A look at how hormones help and hinder diabetes.” Sundays live online at dLifeTV.com at 7 PM ET, 6 PM CT, and 4 PM PT. Keep up on the latest dLife news at dLifeTV.com.

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We can make a difference!

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Dave Joffe, Editor-in-chief

Will you consider switching over your Lantus users to Lilly’s new basal insulin Basaglar, which is not approved as a biosimilar product, but has the same exact properties as Lantus and will likely be less expensive? (follow link to respond)

Congress and the president agreed on a budget for next year that includes big increases to diabetes funding.  The main NIH institution for diabetes research will get over $1.8 billion in funding—an increase of over $68 million compared to FY2015. This will allow the institute to expand promising research that moves us closer toward a cure for diabetes.  The CDC’s Division of Diabetes Translation (DDT) will receive over $170 million—an increase of $30 million.  And the National Diabetes Prevention Program’s budget has been doubled from last year to $20 million.

The new product of the month is the Shoe & Boot Valet. This ergonomically designed product makes it easy to put on shoes and boots without having to bend or reach. Perfect for people with limited mobility like those who have recently had hip or back surgery. The unique patented design makes it easy to remove footwear with one hand. — DoctorsOption

You are reviewing lifestyle modifications with a 42-year-old, relatively sedentary patient who has been newly diagnosed with prediabetes. Your screening for any cardiovascular risk factors was negative, so she has agreed to a 3-month trial of dietary modifications and increased physical activity. Structured exercise interventions and modest weight loss have been shown to lower the risk of developing type 2 diabetes in high-risk populations by an average of: (follow link to answer!)

Those who consumed greater amounts of potato foods, especially french fries, were at an increased risk of type 2 diabetes, independent of BMI and other risk factors. The findings, based on three cohort studies of almost 200,000 U.S. adults, also revealed an association between an increased consumption of potato foods over time and a subsequent increased diabetes risk. In comparison with stable potato consumption, every 3-servings/week increment of potato consumption in four years was associated with a 4% (95% CI 0–8%) higher T2D risk. Replacement of potatoes with whole grains was associated with a lower T2D risk. — Diabetes Care

National cohort study examined events in Medicare beneficiaries.

Quality of life in obese patients with type 2 diabetes improved.

Patients who responded to medication had greater improvement in cardiometabolic risk factors.

Study of 40-year trend focused on three ethnic groups prone to dental complications.

New study shows benefit for patients receiving calcium channel blocker or beta-blocker.

Study shows high carotenoid serum concentration may prevent development of type 2.

Quote of the Week!

“You don’t need a silver fork to eat good food.”

…Paul Prudhomme

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletter:

Janice W. Li,  PharmD intern

Jimmy Tran, PharmD Intern

Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
810 Bear Tavern Road Suite 102
Ewing, NJ, 08628
USA
www.diabetesincontrol.com