Issue 180 Item 7 New Warnings: Potential Iteraction Between Cranberry Juice and

Warning comes from some case reports in Europe.

Cranberry juice is theorized to inhibit the CYP2C9 enzyme that metabolizes warfarin…and INCREASE warfarin’s effects. This is slightly different than the grapefruit interactions. Grapefruit inhibits a different enzyme…CYP3A4.

But the cranberry situation is reminiscent of the early days of the grapefruit interaction. There are more questions than answers. It’s not known how much cranberry juice is needed to cause a problem…or if separating the warfarin and cranberry juice helps. It’s not known if the interaction can happen with other cranberry products…or with cranberry extract supplements.

For now, just keep your eyes open for any potential problems in warfarin patients who consume any cranberry product. Tell them to go easy on the cranberry sauce on Nov. 27. BMJ 2001;322:1571-5 Urology 2001;57:26-9.

================================

Dr. Richard Bernstein’s book the Diabetes Solution NEW AND REVISED
Special Pricing for Subscribers of Diabetes In Control-32% Discount
512 pages packed with new information on Diet, Exercise, Curbing Carbohydrate cravings, new insulin regimens, monitoring blood sugars, helping physicans and patients to regulate blood sugars plus much, much more. “RUN DON’T WALK TO GET THIS BOOK” — Michael R. Eades, M.D. Author of Protein Power. “Please read this book, if you really want to be proactive in the lifelong battle against diabetes and its complication.” — John A. Colwell, M.D., Ph.D., former President, ADA. This book should be in the library of every diabetic patient, and especially Physician’s who treat diabetes.” — Barry Sears, Ph.D., author of THE ZONE. “
More Information: www.diabetes-solution.net