By Sheri R. Colberg, PhD, FACSM
At each dawn of a new year, many people make resolutions to be more physically active—only to fail in changing their lifestyle habits in a sustained manner. Don’t be one of the many who start exercising only to stop again a few months later. Read more about why daily release of feel-good brain hormones is so important and why you should learn how to relax more as well.
Yearly Archives: 2019
Common Diabetes Drugs Linked to Higher Risk of Heart Attack and Stroke
Even though most diabetes drugs can help in managing blood sugar levels, they can also be detrimental to the heart.
Read More »Association Between Use of Sodium Glucose Cotransporter 2 Inhibitors and Serious Adverse Effects
Study findings warrant cautious consideration and discussions about risk vs benefit when considering therapy.
Read More »Time In Range Associated With Diabetic Retinopathy
Study compares enhanced patient care experience with standard shared medical appointments to determine if a significant benefit will result.
Read More »CGM for the Less-Intensive Patient Population
Guest Post by David Kliff, Editor, Diabetic Investor
Although we haven’t gotten there just yet, it’s no longer a question of if type 2’s start using CGM, but when they do and how they use it. CGM is not like an insulin pump when it comes to having a finite market size. CGM is a valuable tool regardless of whether the patient uses insulin.
Antihyperglycemic Therapy
John S. is a 63-year-old Caucasian man with significant abdominal obesity, type 2 diabetes, hypertension, and dyslipidemia as well. On the basis of an exercise stress test, John was recently diagnosed with silent ischemia. John’s current medications include metformin, a DPP-4 inhibitor, an ACE inhibitor/HCTZ agent, a calcium channel blocker, a high-dose statin, and ezetimibe. John’s relevant physical exam and laboratory findings are as follows:
BMI 34.8 kg/m2
Blood pressure 140/86 mm Hg
HbA1C 7.2%
Total cholesterol 150 mg/dL
LDL-C 79 mg/dL
HDL-C 42 mg/dL
Triglycerides 145 mg/dL
non-HDL-C 118 mg/dL
eGFR 65 mL/min/1.73 m2
ACR 100 mg albumin/g creatinine
You explain John’s options for antihyperglycemic therapy. Which of the following answers most accurately describes the extraglycemic benefits of the different options?
A. The GLP-1 receptor agonists may improve endothelial function and reduce infarct size and the SGLT2 inhibitors are likely to improve arterial blood flow.
B. The DPP-4 inhibitors are not safe for people with cardiovascular disease, while the proven cardiovascular benefits of GLP-1 receptor agonists are consistent across the class.
C. DPP-4 inhibitors and SGLT2 inhibitors both reduce blood pressure, which accounts for their similar effects on heart failure.
D. The cardiovascular benefits of both the GLP-1 receptor agonists and SGLT2 inhibitors derive mainly from their effects on weight.
Follow the link for the answer.
Read More »Pump Preference
Which insulin pump do you prefer for most of your patients? Medtronic, Tandem, or Omnipod? Follow the link to share your opinion.
Read More »Diabetes Advisor
Children's Health Diabetes Advisor provides children and families with diabetes a mobile resource to complement the diabetes education programs at Children's Health System of Texas (CHST), providing a one stop source for an Education library and Ketone Manager.
Read More »No Increased Fracture Risk With Canagliflozin in Type 2 Diabetes
Rate of the primary outcome was similar for canagliflozin, glucagon-like peptide-1 agonist
Read More »December 2018 Briefing – Diabetes & Endocrinology
Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for December 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.Three Novel …
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