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Yearly Archives: 2017

Sept. 19, 2017

On most Saturday mornings I go out at 8 AM with our local bike club for a 30 to 40 mile ride. I usually wake up about 6 AM, and will turn on my local NPR station and tune into the People’s Pharmacy. Joe and Terry Graedon have been hosting the show …

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Insulin for Life Answering Calls for Help

Concerned about the extreme weather disasters we have had and those predicted, I reached out to Carol Atkinson, Director of Insulin for Life, a trusted organization, to see how we could help. She was so busy putting packages together for people who have diabetes, she quickly told me the story of Wharton, Texas. It was Labor Day weekend. Hurricane Harvey had just hit and it hit Wharton, Texas hard. They were in need of insulin.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #91: Lipid and Lipoprotein Metabolism, Hypolipidemic Agents, and Therapeutic Goals Part 3

In the fasting state, hepatic VLDL assembly and secretion predominate. Utilization of nascent apo B100 for the assembly and secretion of VLDL is, to a large extent, limited by substrate availability, namely TG, as apo B100 is constitutively synthesized. In the presence of adequate TG, apo B100 is progressively lipidated through the actions of hepatic MTP, and the newly assembled VLDL particle is transported to the Golgi apparatus, where it may undergo further lipidation before secretion into plasma.

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Sept. 16, 2017

There always seems to be a resistance to using newer drugs in combination. Prescribers have never had a problem using metformin in combination with almost any other diabetes medication. Often you will see metformin, basal insulin, and a new drug used, but there has not been a lot of mixing …

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