Many educators and researchers have said that insulin is the best therapy for diabetes patients. When we teach patients how to dose properly, it does make logical sense that insulin indeed is the best. However, there was an interesting presentation at the ADA Scientific presentations that seemed to state the …

Woman, 53 years of age, type 1 diabetes, has been wearing an insulin pump for 18 years. Recently changed insulin pumps. Not only upgraded on a certain brand, but now has a totally different brand. We did not change settings when she started with her new pump. She called to let me know her glucose levels were higher since she has her new pump.

In this exclusive interview from ADA Dr. Israel Hodish discusses the provocative topic "Why insulin therapy doesn't work and what we can do about it," with Steve Freed.

Dr. Israel Hodish talks with Diabetes in Control Publisher Steve Freed at the 2016 ADA Meeting about his ADA presentation on the outcome of patients using insulin and why insulin therapy doesn't work.

In this week's Homerun Slides, the implications for practice and conclusion of the EMPA-REG Outcome Trial.

PI-3 kinase-independent pathways for stimulation of glucose transport: The CAP/Cbl/TC10 pathway. Substantial evidence confirms the presence of PI-3 kinase independent pathways for stimulation of glucose transport. It had long been clear that other growth factor receptors (i.e., the platelet-derived growth factor (PDGF) receptor, cytokine receptors such as IL-4, and certain integrins) activate PI-3 kinase to the same extent as the insulin receptor with generation of PI(3,4,5)P3, yet still do not stimulate glucose transport.