This week’s Clinical Mastery Series newsletter is chock full of great information to help with your patients. First we wrap up our killer Homerun Slides series on DME. Next up is Part 1 of the latest in insulin management techniques from Practical Diabetes Care. Our Disaster Averted works quite well with …

With this week’s Homerun Slides, we wrap up this short series on DME with a case study on how ranibizumab helped one patient who had waited too long for her regular exam, and Dr. Chous gives us a short summary of ways to prevent both DME and the vision loss associated …

David Levy, MD, FRCP Introduction Insulin treatment in type 1 diabetes is substitution/replacement hormone treatment, but replacement is much more variable and difficult to achieve than in other hormone deficiencies (e.g. thyroid, adrenal, gonadal hormones) because of the minute-by-minute variation in insulin secretion by the intact pancreas, which cannot yet be …

About one and a half years ago I was evaluating the educational needs of a mid-30’s, female, hospital in-patient with diabetes mellitus type 2 (DM2). She and her husband both had DM2. Both were slender, active, did carb counting and followed all the prescribed recommendations of living successfully with diabetes. …

A new analysis indicates that people with type 2 diabetes are less likely to suffer myocardial infarctions, strokes, or early mortality when they take blood pressure medications — even if they don’t actually have hypertension…

Why is cancer risk higher among diabetes patients?… Evidence indicates an increased risk of certain cancers among people with type 2 diabetes. Evidence for rarer cancers and for type 1 diabetes is limited. Australian researchers recently explored the excess risk of site-specific cancer incidence and mortality among people with type …

Researchers examined data from 257 randomized trials to find out which drugs cause weight loss… Researchers conducted a systematic review and meta-analysis to summarize the evidence about commonly prescribed drugs and their association with weight change. MEDLINE, DARE, and the Cochrane Database of Systematic Reviews were searched to identify published …

The relatively new long-acting insulin analog needs to be studied to determine its absorption pharmacokinetics… Insulin detemir (IDet) is a relatively new long-acting insulin analog that offers improved absorption pharmacokinetics and slower tissue distribution due to high plasma protein binding. As IDet is increasingly used for treatment of insulin-requiring diabetes, …

Optimum HbA1c level yet to be determined… HbA1c is strongly related to the development of diabetes complications, but it is still controversial as to which HbA1c level to strive for in the treatment of type 1 diabetes. Swedish researchers evaluated HbA1c, followed from diagnosis, as a predictor of severe microvascular …

In the DPP and DPP-OS trials, diabetes was prevented or delayed with metformin or ILS when directed at weight loss and increased physical activity… Previous randomized clinical trials such as the Diabetes Prevention Program and the long-term follow-up trial, the Diabetes Prevention Program Outcomes study, evaluated metformin and an intensive …