In this week’s Homerun Slides, Dr. Stanley Schwartz talks about the Natural History of Type 2 Diabetes and the possibilities for altering the usual development of the disease. He also discusses different strategies for different types of insulin resistance and the implications of this for therapy…. To download these slides in PowerPoint …

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP Dyslipidemia in type 2 diabetes Abnormalities of blood lipids are common in patients with type 2 diabetes, even when there is reasonable glycemic control. The characteristic dyslipidemia of type 2 diabetes consists of elevated very low-density lipoprotein (VLDL) triglyceride (TG) levels, reduced …

In the 24-week study, improved HbA1c and cholesterol reduced the need for medications…   Type 2 diabetes patients are often advised to make dietary decisions that are high in carbohydrates and low in fat and protein. Increased carbohydrates lead to high postprandial glucose readings. Due to this, there is interest …

Lab models that develop diabetes and cancer and that lacked Sirtuin 3 also developed pulmonary hypertension… A University of Alberta team has discovered a protein that is important in the development of pulmonary hypertension which is caused by the narrowing of the blood vessels in the lungs due to excessive …

In patients at high risk of cardiovascular disease, the risk of diabetes was over three times higher in those with increased serum calcium levels… Calcium is needed for the release of insulin to respond to higher amounts of blood glucose. It is possible that if serum calcium is not well …

Deferoxamine delivered through the skin has the potential to prevent amputations… Stanford University School of Medicine researchers presented results at the American College of Surgeons Annual Clinical Congress showing they have developed a drug delivered via a skin patch that can heal wounds and prevent those wounds from reoccurring. Geoffrey …

Pre-diabetes patients show blunted taste response similar to diagnosed diabetes patients…   The decrease in sweet taste sensitivity which can lead to an increase in sugar intake might be a factor driving people with prediabetes to overt diabetes. Researchers assessed the sweet taste sensitivity in pre-diabetics in comparison with diabetics …

Study finds drug combination increases costs and morbidity rates…. In a retrospective cohort study, researchers assessed Texas Medicare claims from 2006 to 2009 for patients 66 years or older who were prescribed glipizide or glyburide and who also filled a prescription for 1 of the 16 antimicrobials most commonly prescribed. …

Smoking during the first trimester may increase risk of type 2 diabetes later in life….

New study found low cognitive function may be a risk factor for diabetes…