Use over 10-year period also leads to cardiac events in type 2 patients using metformin monotherapy… Cardiovascular disease is a common comorbid complication in type 2 diabetes patients. 50-80% of type 2 diabetes patient deaths are a result of a cardiovascular disease. Sulfonylureas are one of the most widely prescribed …

In a study, patients who consumed pistachios showed improvement in fasting glucose, insulin, and HOMA of insulin resistance…. Spanish researchers examined whether a diet rich in pistachios could be beneficial in delaying prediabetes onset and promoting a healthier metabolic profile in patients with prediabetes. A randomized clinical trial was held …

In a large population of obese individuals undergoing bariatric surgery, British researchers found that surgery reduced the incidence of diabetes… They designed a matched cohort study of adults (age 20 – 100 years) identified from a UK-wide database of family practices, who were obese (BMI ≥30 kg/m2) and did not …

Girls whose mothers were also overweight or obese had an even higher risk…. Researchers conducted a study to see if there was an association between hyperglycemia in utero, gestational diabetes mellitus (GDM), and childhood obesity. This research included 421 girls and their mothers in the Kaiser Permanente system in Northern …

Of the 1,174,018 people with diabetes, 63,620 (5.4%) were found to have undiagnosed diabetes. Wherever electronic diabetes registers are used to support the provision of care, and where blood glucose levels, HbA1c and quality-of-care data are recorded in the same system, it should be possible to identify readily (and at …

The Innovative Network for Sight (INSIGHT) study included 1,894 people (with an average age 53 to 55 years) who were screened across the sites; 21.7 percent of the individuals were found to have DR in at least one eye, according to the study results. Background DR was the most common …

Researchers have identified a small protein with a big role in lowering plasma glucose and increasing insulin sensitivity. The report indicates that Sestrin 3 – found to operate in multiple biological processes, including resistance to oxidative and genotoxic stresses, protection against aging-related pathologies, and promotion of metabolic homeostasis – plays …

Ambio Remote Health Monitoring System  The Ambio Remote Health Monitoring System, which has FDA 510(k) clearance, wirelessly sends readings from devices such as a weight scale and blood pressure and blood glucose meters to the web-based Ambio Care Portal where the readings can be viewed by patients and their authorized …

French Company Granted Rights to Implantable Pump Sevier, a pharmaceutical company based in France, agreed to make payments totaling over $1B to privately held Intarcia Therapeutics, Inc. for the rights to co-develop the company’s implantable pump, designed to deliver one year’s worth of the GLP-1 exenatide.

A couple of questions came up last week during a review of SGLT-2 inhibitors by my interns.  The first question had to do with what was happening with SGLT-1 receptors in the research, as one of the students had remembered that there are 8 or more DPP receptors and wondered …