Pioglitazone (Actos) and rosiglitazone (Avandia) appear to substantially boost risk of macular edema in type 2 diabetes, an observational study found. Incidence of diabetic macular edema was 1.3% at 1 year on a thiazolidinedione (TZD) compared with just 0.2% among type 2 diabetes patients not on one of those agents. …

Omega-3 fatty acids did not reduce the rate of cardiovascular events in high-risk patients with prediabetes or diabetes followed for half a dozen years, the randomized ORIGIN trial found. Cardiovascular deaths occurred among 9.1% and 9.3% of those randomized to n-3 fatty acids or placebo, respectively. N Engl J Med 2012 

Statin drugs may leave users — especially women — feeling drained and tired on exertion, a clinical trial suggested. Combined scores for change in energy and exertional fatigue worsened after starting a statin compared with placebo (P=0.005). For women, scores suggested that as many as 40% felt more tired and …

Daily insulin glargine injections, begun during the early stages of type 2 diabetes, neither increased nor reduced the risk of heart attacks, strokes, cancer or cardiovascular-related mortality, researchers found in the largest and longest study of its kind….

The ORIGIN study also examined whether daily insulin use in people at high risk for type 2 diabetes would prevent or slow progression of the disease….

In a modern-day clinical trial of a medicine belonging to one of the world’s oldest classes of drugs, researchers have found that a drug related to aspirin and salicylate, may be a potential treatment for people with type 2 diabetes….

Many are unable to control A1c and many develop markers of risk for cardiovascular complications….

In the most comprehensive analysis of people with type 1 diabetes ever undertaken in the U.S., researchers found that….

Eating breakfast is associated with a decreased chance of developing type 2 diabetes….

Achieving normal glucose regulation even once predicted a lower risk of progression to diabetes for prediabetic patients. The evidence points to working hard at prediabetes to get rewarded both now and later….