Statin drugs may leave users — especially women — feeling drained and tired on exertion, a clinical trial suggested. Combined scores for change in energy and exertional fatigue worsened after starting a statin compared with placebo (P=0.005). For women, scores suggested that as many as 40% felt more tired and fatigued during physical activity on simvastatin (Zocor) than without the lipid-lowering medication, the group reported. Arch Intern Med 2012
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