Isis Pharmaceuticals, Inc. announced it has initiated a Phase 1 study of ISIS-SGLT2Rx, an antisense drug that inhibits the production of sodium dependent glucose co-transporter type 2 (SGLT2). This first in class diabetes drug, causes you to urinate your excess glucose.

Scientists have produced results that could silence the current debate about exactly how fat molecules clog up muscle cells, making them less responsive to insulin. The finding is an important milestone in understanding the mechanisms of obesity related insulin resistance, a precursor of Type 2 diabetes.

Researchers in 20 medical centers across the country are enrolling adults with type 2 diabetes who have poorly controlled blood glucose to participate in a clinical study, Targeting Inflammation with Salsalate in Type 2 Diabetes (TINSAL-T2D).

People who sit down to a daily breakfast of eggs may have an increased risk of developing type 2 diabetes, new research suggests.

In study, aerobics, resistance training lowered risk of insulin resistance and improved motor function.

Diabetes increases the risk for dementia, including vascular dementia and Alzheimer’s disease (AD), by 125%, especially if onset is in midlife, a population-based study suggests.

Older adults appear more likely to quit smoking or lose weight following a recent diagnosis of heart disease, diabetes or another serious condition, according to a new report.

Patients with high cholesterol levels who continually take statins appear to have a lower risk of death over four to five years, regardless of whether they already have diagnosed heart disease, according to a report

A key protein in the immune system pathway that effects the pancreas discovered.

Treatment of mild gestational diabetes yields clinical benefit, a randomized trial showed. Although a composite endpoint of neonatal morbidity did not differ between the treatment group and the controls, rates of Caesarean delivery (P=0.021) and shoulder dystocia (P=0.019) were significantly reduced by treatment.