In part one of this special interview, Dr. Mark Mattson and DIC publisher Steve Freed discuss Dr. Mattson’s research into brain aging and neurodegenerative disorders, and the positive effects of intermittent fasting in delaying aging and preventing diabetes.
To read the transcribed interview:
View other videos in the series:
- Part 1: Intermittent Fasting: What is it? Recommend it?
- Part 2: Where and How Can We Start the Intermittent Fasting Program?
- Part 3: Preventing CVD, Diabetes, Alzheimers, and Many More Diseases
- Part 4: Studies on Intermittent Fasting
- Part 5: Searching for Proof of Disease Prevention
- Part 6: Getting Started with Intermittent Fasting
- Part 7: In the Event of a Diagnosis
- Part 8: Appetite Suppressants
Excerpt from transcript: Mark Mattson intermittent fasting comments:
“Well, there’s a lot of active research going on in this area moving to studies of human patients. Most of the work is in animal models but there are initial studies that support those statements in human populations. And most of these studies involve what we call intermittent fasting approaches in which, for example, a person two days a week will eat nothing or very little on those days and stay hydrated.
And another approach is restricting the time window each day during which food is consumed, for example six to eight hours. It turns out most Americans put something caloric in their mouth when they get up and then they eat meals, snacks and they eat something right before they go to bed, so the only time they’re not taking in anything caloric is when they’re sleeping.
And it turns out one reason that we think that fasting, even for relatively short time periods like 16 or 24 hours may be beneficial for diabetes is because it greatly improves insulin sensitivity established in numerous animal studies and in at least half-a-dozen human studies.
But also if you eat regular meals – three meals a day plus snacks – you never tap into your fat stores as an energy source because every time you eat energy goes into your liver and that’s always used first; so with fasting, even relatively short fasts, you shift to burning fats and this seems to contribute to the beneficial effects on body weight and the, if you will, anti-diabetic effects of intermittent fasting.”