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Cardiovascular


Table of Contents

Articles

Fatty Liver Disease Tied to Diabetes, Atherosclerosis

Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of both type 2 diabetes and carotid atherosclerosis, according to two studies.... 


AHA Questions Salt Intake Study

The American Heart Association questions the findings of a new analysis suggesting that most people around the world are consuming just the right amount of sodium.... 


Vitamin D Not Linked with Heart Risk in Men

Circulating levels of vitamin D had no apparent influence on overall risk for cardiovascular disease in older men.... 


Benefits of ARBs Not the Same as ACE Inhibitors

The effects of ACEIs and ARBs on multiple outcomes in type 2 diabetes patients.... 


Negative Outcomes Associated with Inter-arm Systolic Blood Pressure Differences in Diabetes Patients

Inter-arm systolic blood pressure differences may be a sign of bad things to come....


Lifestyle Changes during Prediabetes Can Reduce Mortality

Not only may an intensive program of diet, exercise, or both delay progression from prediabetes to diabetes, but among women, it may also lower CVD and all-cause mortality.... 


Diabetes and CVD Risk with Postpartum Weight Gain

Failure to lose 'baby weight' may carry long-term risk for diabetes and heart disease.... 


Aleglitazar Does Not Reduce Risk of Recurrent CV Events among Diabetes Patients

The use of aleglitazar does not appear to reduce the risk of cardiovascular events in diabetic patient.... 


Strong Association between Mediterranean Diet and Lower Risk of Diabetes

The benefits of the Mediterranean diet appear to be the same cross-culturally… 


Severe Hypoglycemia Increases Premature Death and Cancer Risk in T2DM

A look at whether type 2 diabetes patients with severe hypoglycemia exhibit certain phenotypes that may predict premature death and all-site cancer....


Phentermine/Topiramate Slows Progression to T2DM

Cardiometabolic risk factors also significantly improved....


Who Qualifies for Statin Treatment under the New Guidelines?

The new guidelines from the ACC and AHA would increase the number of individuals eligible for statin therapy by nearly 13 million people.... 


Is Moderate Wine Consumption in Type 2 Diabetes Beneficial?

Moderation is key when it comes to diabetes and alcoholic beverages.... 


Statin Users Can Experience Weight Gain with Diabetes Onset

Statins will lower cholesterol and increase weight in diabetic patients.... 


Multifactorial Treatment Effective at Improving Prognosis in Those with Diabetic Nephropathy

Cohort study determines how patient outcomes have changed since multifactorial treatment of CV risk factors and RAS inhibition have become standard of care.... 


Hyperglycemia in the Hospital Can Lead to Diabetes in the Future

Myocardial infarction (MI) patients who are hospitalized and are hyperglycemic may have increased risk for diabetes.... 


Poor Glycemic Control and Insulin Resistance Associated with Vascular Endothelial Dysfunction

Poor glycemic control is associated with the occurrence of morning blood pressure surge (MBPS), which is thought to be involved in the development of vascular dysfunction....


Arterial Stiffness Associated with Glucose Tolerance in Hypertensive Patients

Researchers find that increases in arterial stiffness may occur in hypertensive patients other than those with T2DM.... 


Gestational Diabetes and the Risk of Heart Disease

According to research by the American Heart Association, pregnant women who develop gestational diabetes may be at an increased risk of developing atherosclerotic complications, such as heart disease, later in life.... 


Do Saturated Fats Really Cause Heart Disease?

An international research collaboration led by the University of Cambridge analysed existing cohort studies and randomised trials on coronary risk and fatty acid intake. They showed that current evidence does not support guidelines which...


No CVD Benefit for Older Patients Taking Omega-3 Fatty Acids

Taking omega-3 fatty-acid supplements for nearly five years failed to reduce the incidence of CVD mortality, MI, stroke, unstable angina, revascularization, CHF hospitalizations, and resuscitated cardiac arrest, report...


Visit-to-Visit Variability in Systolic BP a Risk Factor for Diabetic Nephropathy

Research shows that variations in SBP can negatively impact the development and progression of diabetic nephropathy in type 2 diabetes patients.... 


Certain Complications of Obesity May Be Linked to Pollutants

Persistent organic pollutants (POPs) are found to be prevalent in individuals with cardiometabolic complications.... 


High-protein Diet in 40's and 50's May Increase Risk for Diabetes, Cancer, and All-cause Mortality

But for those over 65, a higher protein intake may be beneficial....


Childhood Obesity May Increase Cardiac Events in Adulthood

Even if their weight is under control, adults who were obese as children may be at higher risk for cardiac events and early death....


Diabetes Clinical Case Series, Excerpt #8, Endocrinology and Diabetes

Oliver, aged 46, is found to have...


Older Patients with T2DM and Comorbidities Don't Feel Heard

Responses in focus groups point to a "disconnect" between patients with these conditions and their providers.... 


UK NICE Guidelines Advise for Wider Use of Statins

CVD preventive treatment should also be started much earlier in patients with lower risk.... 


FDA to Review DPP-4 Inhibitor Saxagliptin for Increased Heart Failure Risk

SAVOR (Saxagliptin Assessment of Vascular Outcomes Recorded in patients with diabetes mellitus) trial showed a 27% increase in hospitalizations for heart failure among patients receiving saxagliptin as opposed to...


New Non-invasive Methods Detect Microvascular Changes in Type 1's

Noninvasive capilaroscopy, laser Doppler flowmetry, and retinal imaging among techniques used….  


Diabetes during Puberty Increases Risk of Complications

Girls with diabetes are at an even greater risk for excessive weight gain during puberty....


Do Incretin Medications Improve Cardiovascular Disease?

The effects of GLP-1 agonists and DPP-IV inhibitors on cardiovascular safety.... 


Updated Recommendations on Aspirin Therapy in Diabetic Patients

An overview on aspirin use in the prevention of cardiovascular events.... 


The "Obesity Paradox" in Type 2 Diabetes

Increased mortality from cardiovascular outcomes found in overweight patients but.... 


Type 2 Diabetes and Mortality Risk

Approximately two-fold increase.... 


Can Diuretics, Statins, and Beta Blockers Increase Diabetes Risk?

In an analysis of the NAVIGATOR study, patients who already had an impaired glucose tolerance at the beginning of the trial were shown to have.... 


Statins and Type 2 Diabetes

Effects of treatment with pravastatin, atorvastatin, and pitavastatin examined....


Diabetes Clinical Case Series, Excerpt #6, Endocrinology and Diabetes

Ramzi Ajjan, MRCP, Med Sci, PhD


The Mediterranean Diet Again Shows Positive Gains in Preventing T2DM

Adopting a Mediterranean diet rich in extra-virgin olive oil may protect people at high risk for heart disease against diabetes.... 


Adhering to Diet Recommendations Lowers Metabolic Syndrome Risks

Risks of developing coronary artery risk disease, type 2 diabetes and stroke decrease with better adherence to diet and nutrition recommendations.... 


Does Racial Disparity Affect Quality in Cardiac Surgery?

Hospital quality was associated with racial disparities in outcomes after coronary artery bypass graft (CABG) surgery.... 


Getting Closer to a Possible Cure

University of Missouri School of Medicine researchers have received three U.S. patents for methods that cured type 1 diabetes in mice via a major discovery....


ADA's 2014 Standards of Care Released

The American Diabetes Association has released their annually revised Standards of Medical Care in Diabetes for 2014, with an emphasis on individualized treatment of diabetes.... 


Can Periodontal Therapy Improve Diabetes Control?

In a new trial, researchers find that normal periodontal therapy doesn't improve glycemic control for patients with type 2 diabetes. However, our Advisory Board member, Maria Ryan, DDS, PH.D, has a somewhat different take on these...


HbA1c and Heart Failure Risk

Diabetes is an independent risk factor for heart failure (HF) but can tight glycemic control reduce the occurrence of HF among diabetic patients?... 


Study Indicates that Diabetes Medication Reduced CVD Hazard Rate 53% in Type 2 Diabetes Subjects Taking Metformin

Metformin plus Cycloset shows significant CVD risk reduction for type 2 diabetes patients in trial....


JAMA Issues New Blood Pressure Guidelines

Slightly higher BP in older adults is acceptable....


Metformin's Impact on the Heart Differs in Men and Women

Study showed positive impact for women with type 2 diabetes but….


The Shift from T1 to T2 in the Youth Population

Is diagnosis of type 2 more dangerous in youth?...


Diet Drinks and Cardiometabolic Disease

What the studies really say.... 


Pros and Cons of Pioglitazone

Should it be used in treating type 2 diabetes?... 


Exercise vs. Medications on Mortality Outcomes

Researchers may be concentrating so much on pharmaceutical interventions that they are neglecting the health benefits of exercise....


Fenofibrate a Treatment for Diabetic Retinopathy

Multiple studies show possible benefit of using fenofibrate in diabetic retinopathy....


Explanation for the CHD Risk in Individuals with High BMI

Three specific factors explained why these patients have a higher risk of CHD events....


The Link between Memory and Statins

Systematic review relates information regarding the link between memory and statin use....


Achieving CV Goals with Weekly Exenatide vs. Sitagliptin or Glargine

Once-weekly exenatide shows benefit in type 2 diabetes patients.... 


The Impact of Hypoglycemia on Cardiovascular Risk/Mortality

Intensive blood sugar goal may not be the answer.... 


FDA Lifts Prescribing Restrictions on Avandia

The FDA has lifted the restrictions on the prescribing and use of the diabetes drug rosiglitazone on the basis of recent data that demonstrate no elevated cardiovascular risk.... 


Chelation Therapy Shows Marked CV Event Reduction in Diabetic Patients

The initial TACT report showed a significant interaction of EDTA therapy and the diagnosis of diabetes mellitus.... 


Cardiovascular Events and HbA1C levels in Diabetic, Dialysis Patients

Glycemic control for diabetic, dialysis patients linked to cardiovascular events.... 


Combination Therapy Has Increased Risk in Diabetic Patients

No benefit seen from the combination therapy of an ACE inhibitor and ARB....


New Guidelines for Cardiac Prevention and Statin Use

New guidelines abandon LDL targets and identifies the four major primary and secondary patient groups who should be treated for statins....


A Clear Choice for Diabetes Patients with Hypertension

Study looks at effects of different classes of antihypertensives for diabetes patients....


Insulin-Treated Diabetes Patients with CAD

A sub group analysis from the FREEDOM trial shows the impact of insulin-treatment status when undergoing CABG or PCI....


GLP-1 Serum Levels Associated with Coronary Artherosclerosis

Prior reports of GLP-1 vasoprotective effects may not be valid....


Heart Disease Increases in Women with Diabetes

Women with diabetes have a greater risk of heart disease than men....


Testosterone Therapy in Veterans Causing Adverse Outcomes

Treating low levels of testosterone is associated with increased risk of adverse outcomes....


Can Acarbose Slow Progression of Thickening of the Carotid Artery Wall?

Acarbose treatment shows major benefits for type 2s.... 


Type 2 Youths Get Earlier Onset of Complications than Type 1's

The onset of diabetes complications appear much earlier in youth with....


HbA1c Variability a Predictor for Macrovascular Complications in Type 2's

HbA1c variability may not impact CVD.... 


Bypass Surgery Helps Improve Diabetes Control

Gastric bypass surgery improves glycemic control levels and significantly reduces weight.... 


Diabetes-related Complications Increase Risk of Stroke

Type 1 diabetes patients were more likely to have had a stroke if they had blood vessel-related kidney and eye damage.... 


Saturated Fat Not the Cause of Heart Disease

It is time to bust the myth of the role of saturated fat in heart disease, argues Aseem Malhotra, interventional cardiology specialist registrar at Croydon University Hospital in London, in an Observations piece in BMJ.... 


Statins May Increase Risk of Cataracts for Older Patients

Several risk factors for CV disease are also risk factors for cataract.... 


The Final Word on Coffee Consumption and Heart Health

Effects on hypertension, insulin sensitivity, serum lipids, CHD, CHF, arrhythmias, stroke and mortality....


Diabetes Mellitus a Prognosis in CHF

DM associated with increased risk of death in congestive heart failure (CHF) patients....


Is Vigorous Physical Activity Better than Moderate Physical Activity for Women?

It has not been demonstrated that in overweight or obese people high-intensity interval training is better than moderate-intensity exercise in inducing weight loss except for....


Iron Deficiency Impacts Health Related Quality of Life

In patients with CHF, ID but not anemia was associated with reduced HRQoL (health related quality of life), mostly due to physical factors....


Does Retirement Affect Adherence to Medications?

There is a decline in adherence to medication after retirement among men and women with hypertension and men with type 2 diabetes....


Combination Drug Shows Lower Heart Risk

Rosiglitazone plus exenatide shows lower percentage of MI.... 


Vitamin D Supplementation Reduces Insulin Resistance in T2DM

Cholesterol levels unchanged....


Dissecting Dietary Determinants of Atherogenic Dyslipidemia and Targeting the Culprit Particles

Joy Pape, RN, BSN, CDE, WOCN, CFCN, FAADE Dr. Ronald Krauss, MD, Senior Scientist and Director of Atherosclerosis Research at...


Joslin's Diabetes Deskbook, Updated 2nd Edition, Excerpt #32: Macrovascular Complications, Part 4

Richard S. Beaser, MD Michael Johnstone, MD


Joslin's Diabetes Deskbook, Updated 2nd Edition, Excerpt #31: Macrovascular Complications, Part 3

Richard S. Beaser, MD Michael Johnstone, MD


Joslin's Diabetes Deskbook, Updated 2nd Edition, Excerpt #30: Macrovascular Complications, Part 2

Richard S. Beaser, MD Michael Johnstone, MD


Top Ten Things to Know: 2011 Effectiveness-Based Guidelines for the Prevention of CVD in Women

  In 2007, CVD caused about 1 death per minute among women in the US.


Top 10 Sodium Overkill Culprits (Patient Handout)

  Nine out of 10 Americans consume more sodium than they need, according to a new report...


Why Heart Rate Variability Is Key to Longevity and Healthy Aging

 


SPECIAL FEATURE: GLP-1 Agonist-based Therapies: An Emerging New Class of Antidiabetic Drug With Potential Cardioprotective Effects

Melanie Sulistio, MD, Curtis Carothers, MD, Mandeep Mange, BS, Mike Lujan, BS, Rene Ofiveros, MD, and Robert Chilton, DO PART 2: GLP 1 Agonist-based Therapies: How do they reduce...


United States of Diabetes Report

  You can use the information in this report to provide evidence for your ...


Psychology in Diabetes Care, 2nd. Ed, Part 9

Edited by Frank J. Snoek and T. Chas Skinner Diabetes in Adolescents


Managing Clinical Problems in Diabetes, Case Study #9: Mrs. MS

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


Body Fat Calculator

  People ...


PRADAXA (DABAGATRAN), A New Anticoagulant for Stroke and Embolism Prevention

By Jennifer Freidman 2011 Doctor of Pharmacy Candidate, University of Florida Atrial fibrillation currently affects about 2.2 million Americans. If left untreated it can cause embolism ...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 15, Pt2

Long-Term Complications and Treatments: Dyslipidemia


New Product: How high is your blood pressure? Ask your iPhone‎

How high is your blood pressure? Ask your iPhone‎ iHealth Lab has announced the iHealth...


A Year of Diabetes Research 2010

Prevention, therapy and complications are the keystones for diabetes research. It would be impossible to cover all of the developments in just one feature. So here is a brief summary of some of the best for 2010.


Editor's Note: Diabetes and Cardiovascular Disease, Lifestyle Habit Changes, and More....

Every week there is a new study coming out showing the relationship between diabetes and cardiovascular disease. There are over 1.1 million Americans who will have a serious heart attack in 2011 and there are over 80 million who have one or more...


Hyperglycemic Emergencies

Lana Kravarusic Doctor of Pharmacy Candidate, University of Florida 


Letter from the Editor, August 29, 2010: Popeye vs Wimpy

It appears there is a classic battle brewing between Popeye and Wimpy as to what works better for your health.  Popeye thinks he was right when he said, "I'm strong to the finich, 'Cause I eats me spinach," as a new study of over 220,000...


Heart Risk from Actos® as Great as from Avandia®, Study Suggests

According to a study published in Circulation: Cardiovascular Quality and Outcomes, the heart risk from Actos is just as great as the risk posed by Avandia according to a story published Tuesday, August 24 by the Los Angeles...


Essential Oils for the Management of Type 2 Diabetes

Ivory A. Gordon, Pharm.D....


America's Silent Killer: Oprah and Dr. Oz Want to Save Your Life

By...


Preventing Medication Errors

Institute for Safe Medication Practices


The Glucose – CVD Connection: The Search For The Missing Link

There is a new study out trying to show the link between intensive glycemic control and reductions, if any, in cardiovascular endpoints. The VA Diabetes Trial of 1,800 patients, showed like other, larger trials recently published, that there was no...


The Message for World Kidney Day 2009:

Hypertension And Kidney Disease: A Marriage That Should Be Prevented is the message for WORLD KIDNEY DAY 2009 and we have a special feature written jointly by Eberhard Ritz representing the International Society of Nephrology (ISN) and George...


HIV-infected patients are at an increased risk for developing Diabetes

More and more patients with HIV are controlling their disease well. When viral loads are under control, patients often are seen by clinicians for other problems. Diabetes seems to be one of those problems that get a lot of attention. My current...


Risks for Drug Induced Pancreatitis

With all the press lately about the incretin mimetics and pancreatitis our current intern, Jennifer Webb, PharmD Candidate, FAMU has taken a look at the facts, and compared the chances of pancreatitis among classes of drugs and how the risk of...


Charcot Foot: A Potenial Risk Factor for Diabetic Patients

Charcot Foot: A Potential Risk Factor for Diabetic Patients, is a valuable report on an under diagnosed problem written by Jennifer Webb, Doctor of Pharmacy Candidate, FAMU. You may want to print this out and hand it to your patients.


Presentations

Therapy of Type 2 Diabetes Mellitus, Update, Part 2

  In this week's set of Homerun Slides from Dr. Stanley Schwartz, we delve into the current state...


Quality Measures In Cholesterol and Diabetes Management, Part 1 of 4

  This week we have the first set of slides in a three-part series examining current treatment practices...


Hypertension in the Medicare Population, Part 2 of 2

In this second set of Homerun Slides on Hypertension in the Medicare Population, we review some...


Hypertension in the Medicare Population, Part 1 of 2

  In this week's Homerun Slides set, we take a look at the challenges posed by an increasingly...


Achieving Glycemic Control in the Hospital Setting, Part 3 of 4

In this week's set of Homerun Slides, our topics include IV Insulin Protocols, Considerations when...


Diabetes Mellitus 101 for Medical Professionals, Part 5 of 9

In this week's Homerun Slides, we cover such topics as the Potential Mechanisms of...


Diabetes Mellitus 101 for Medical Professionals, Part 2 of 9

In this week's set of Homerun Slides,...


Sleep Apnea

If your diabetes patients have sleep apnea, they may also have hypertension....


Diabetes Microvascular Complications, Part 1 of 2

Diabetes mellitus can lead to many acute and chronic complications. The chronic...


Understanding Acute Coronary Syndrome

Over twelve and half million Americans currently have heart disease and 1.1 million...


Insulin Resistance, Part 2 of 3: Inflammation Markers

Plasminogen is an acute phase protein and precursor to plasmin, which...


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