Main Newsletter
Mastery Series
Therapy Series
 

Cardiovascular


Cardiovascular Health and Diabetes

Diabetes is an inflammatory, cardiometabolic disease. It elevates nearly every cardiovascular risk factor, and most diabetes patients will die from cardiovascular disease. However, insights from new clinical research along with patient education provide new edges to improve cardiovascular outcomes in your diabetes patients. Learn more here and in our weekly newsletters.

Table of Contents

Articles

PPAR Agonists Raise Heart Failure Risk for Pre-diabetic and T2DM Patients

In the meta-analysis of 14 randomized trials, DPP-4 inhibitors were also found to increase cardiovascular risk slightly while the effect of insulin glargine was neutral….


Drinking Coffee Results in Less Calcium Buildup in Arteries

Three to five cups daily may reduce risk of heart disease...


Reducing Atherosclerosis in Type 2 Diabetes with Treatment According to Guidelines

After two years of follow-up, total wall volume of the carotid artery in type 2 diabetes patients decreased by 9.6% (p = 0.016) with treatment according to the cardiovascular risk guidelines. In non-diabetic controls, risk was...


Are Lower Urinary Tract Symptoms Linked to Incidence of Type 2 Diabetes and Heart Disease?

Occurrence of lower urinary tract symptoms might be a useful predictor...


Even Without HTN, BP Meds Benefit Diabetes Patients

A new analysis indicates that people with type 2 diabetes are less likely to suffer myocardial infarctions, strokes, or early mortality when they take blood pressure medications -- even if they don't actually have hypertension…


Deaf People at Higher Risk of Type 2 Diabetes

Inadequate access to primary care means that deaf people have a higher risk of developing type 2 diabetes, high blood pressure, and heart disease...


Effects of Prediabetes on Subsequent Cardiovascular Disease and Diabetes

In this longitudinal population-based study, 1609 patients were followed between 2002 and 2014 (mean, 10.9 years) to determine whether prediabetes affected risk for cardiovascular disease (CVD) or diabetes mellitus (DM)...


Blood Pressure Lowering in Type 2's Leads to Lower Risk of CVD and Improved Mortality

Blood pressure-lowering treatment among patients with type 2 diabetes is associated with a lower risk of cardiovascular disease (CVD) and heart disease events and improved mortality, according to a study…


Measuring CKD and Cognitive Impairment in Type 2 African Americans

Participants with CKD had significantly poorer processing speed and working memory….


More Leisure-time Physical Activity Results in Less Short-term Cardiovascular Risk in CAD Patients

Both patients with and without diabetes but with thrice-weekly physical activity had reduced risk of cardiovascular events compared with patients with reduced physical activity….


Obesity and CHD Association in Type 2 Diabetes Patients

Are obesity and CHD truly associated?...


Treat the Whole Patient, Not Just Part

We were running a clinical study on erectile dysfunction. An obese 68-year-old male came in looking for help for his ED, so he thought he might qualify for the study. He had not had a medical workup for some time and wasn't aware of any underlying...


Acarbose Higher Cardiovascular Risk Than Metformin

According to a new retrospective study acarbose may not have a cardioprotective effect as good as metformin when used as first-line therapy…


Beloranib Demonstrates Weight Loss in Hypothalamic Injury-Associated Obesity

The drug, a first-in-class MetAP2 inhibitor, was well-tolerated and also improved cardiovascular disease risk factors...


Healthy Lifestyle Choices Key in Prevention of CVD among Young Women

Healthy behaviors including weight control, moderate physical activity, and minimizing TV watching can avert up to 73% of CHD cases among women over 20 years...


ADA's Revised Diabetes Standards Increase Statin Use

New guidelines call for giving the cholesterol-lowering drugs to almost all people with diabetes to help prevent heart disease...


Patients Can Lose Years of Life Because of Excess Weight

A team of Canadian researchers found that as many as 8 years could be lost by men and the effects of overweight and obesity were greatest for younger patients. 


Even Mild Stenosis Linked to Death in Diabetes

Long-term registry shows impact similar to single-vessel obstruction...


Increased Mortality with Combining Sulfonylurea and Insulin

About 11,000 patients using both insulin and sulfonylurea were evaluated...


Statin Therapy Does Not Reduce Risk of Fracture

In an analysis of data from the JUPITER trial, higher baseline hs-CRP level was also not associated with an increased risk of incident fracture...


Are There Good and Bad Carbs for Patients with Diabetes?

New research suggests that for non-diabetic people who follow a healthful diet, the glycemic index may not be very important...


Hypoglycemia Increased Risks for CV Events, Death in Diabetic Patients on Insulin

Increased risk seen in both type 1 and type 2 diabetes patients treated with insulin.


Cinacalcet May Protect Against Fracture in Dialysis

Mortality, cardiovascular disease risk remains same for patient with secondary hyperparathyroidism...


Blocking the Blood Vessel Dysfunctions That Occur in Diabetes

Too much circulating sugar and fat can cause the endothelial lining to become inflamed....


Low Testosterone Causal Lead to Type 2 Diabetes Unclear

More studies needed to determine effect on adverse clinical outcomes….


ACCORD Analysis Suggests Intensive Glucose Lowering May Reduce Ischemic Cardiovascular Events

Higher A1C target recommended for patients over 65 with comorbidities…


Inconsistent Evidence that Testosterone Increases CV Risk

EMA committee recommends that medication labels be changed to reflect more accurate data….


Carbs Associated with Higher Diabetes and Heart Disease Risk Factor

Lowering saturated fat intake did not lower saturated fat blood levels but increasing carbs raised levels of palmitoleic acid, a fatty acid associated with disease...


Study: Once-daily, Low-dose Aspirin Does Not Reduce Risk of CV Death

There is some level of risk of CVD events that would result in a positive trade-off of benefit and risk for the use of aspirin, but the precise level of risk is remains uncertain....


Excess Mortality from Cardiovascular Causes in Type 1 Diabetes

Degree of glycemic control is investigated for excess risk of death due to cardiovascular cause....


IMPROVE-IT Trial Summary

Adding ezetimibe to a statin therapy (simvastatin) shows superior results in the reduction of CV events compared to statin therapy alone....


HDL Measurement Provides New Powerful Information

Cholesterol efflux capacity appears to be superior for indicating cardiovascular risk and better target for therapeutic treatments than standard measurements....


Handbook of Diabetes, 4th Ed., Excerpt #19: Macrovascular Disease in Diabetes

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP


Severe Hypoglycemia Associated with CV Mortality Risk in Type 1

A previous history of severe hypoglycemia is linked to increased death rates after a cardiovascular event in type 1 diabetes patients...


Link between Free Fatty Acids and Acute MI, Type 2 Diabetes

Free fatty acids may play an important role in the development of diabetes and cardiovascular diseases...


PAD, Heart Failure Shown Most Common Cardiovascular Disease Outcomes

Prevention methods differ from standard stroke and myocardial infarction presentations in T2DM patients...


Handbook of Diabetes, 4th Ed., Excerpt #18: Hypertension in Diabetes

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP


Sulfonylureas Linked to Cardio Disease in Women Without Prior Incident

Use over 10-year period also leads to cardiac events in type 2 patients using metformin monotherapy...


Editor's Note, DCMS #214

The prevailing statistics say that 74% of all diabetes patients have high lipids, 75% have hypertension, and that 56% of all diabetes patients have both conditions. If you take the time to read all of this week's clinical newsletter you will learn...


Handbook of Diabetes, 4th Ed., Excerpt #17: Blood Lipid Abnormalities

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP


Protein Discovered that May Link Diabetes, Cancer and Pulmonary Hypertension

Lab models that develop diabetes and cancer and that lacked Sirtuin 3 also developed pulmonary hypertension…


High Serum Calcium Linked to Type 2 Diabetes Incidence

In patients at high risk of cardiovascular disease, the risk of diabetes was over three times higher in those with increased serum calcium levels...


The Impact of Physical Activity on Young Type 1 Diabetes Patients

Physical activity intervention had a positive impact on reducing HbA1c, BMI and total cholesterol but insulin dosage did not change in the study...


Possible Link between Diabetes and the Hardening of Heart Valves

High blood glucose levels over a long time might be responsible for aortic valve calcification...


Hyperglycemia and Incidence of Subclinical Myocardial Damage

Hyperglycemia associated with myocardial damage appears to begin before the diagnosis of diabetes and requires a highly sensitive assay to detect it...


The Efficacy of Beta Blockers in Patients with and without MI

Can beta blockers lower cardiovascular events...


Stricter Glycemic Control after Coronary Artery Bypass Surgery Evaluated

Prospective study shows that maintenance of glucose levels in a liberal target range is safer and more beneficial than a tight target range after CABG...


Low Testosterone Increases Risk of Atherosclerosis for Men with Diabetes

Men with low testosterone have more than a 40% higher relative risk than men with normal testosterone...


The Impact of Mediterranean Diets on Metabolic Syndrome

A supplemented Mediterranean diet can lead to metabolic syndrome reversal....


Longer Working Hours Associated with Higher Type 2 Incidence

Socioeconomic status plays a role in how strong the association is....


Gastric Bypass Better than Gastric Band for Long-Term Results

Gastric bypass surgery shows better outcomes for long-term weight loss, controlling type 2 diabetes, hypertension, and cholesterol level....


SGLT-2 Inhibitor May Reduce Blood Pressure for Type 2s

SGLT-2 inhibitor use in the management of glucose in type 2 diabetes could reduce blood pressure in patients with hypertension....


Handbook of Diabetes, 4th Ed., Excerpt #13: Control and Complications

Rudy Bilous, MD, FRCP Richard Donnelly, MD, PHD, FRCP, FRACP  


Tight Blood Sugar Control May Not Be Needed for Heart Bypass

Survival rates similar for those with looser glucose limits.... 


EASD: Insulin Pumps Lower Mortality Rate 29% Compared to Multiple Injections in T1DM

And fatal cardiovascular disease risk is 43% lower for type 1 diabetes patients using insulin pumps over multiple daily injections.... 


EASD: Type 2 Diabetes plus Ischemic Heart Disease Can Predict Mortality

Long-term mortality of patients with ischemic heart disease is independently predicted by diabetes....


No Mortality Reduction in Type 2 Diabetes with Tight Glycemic Control

No effect of tight glycemic control on mortality or major cardiovascular events in long-term follow-up of the ADVANCE trial.... 


No Risk Seen of CHF with Incretin-Based Drugs in T2DM

A large study in the UK looked at the long-term effects of GLP-1 and DPP-4 therapy on patients' risk of congestive heart failure....


Effect of Low HDL Cholesterol on Cancer Risk in Type 2 Diabetes Patients

Low HDL increases the risk of heart disease but does it also increase the risk of cancer?...


Statins May Protect against Microvascular Complications of Diabetes

Complications that can lead to blindness, nerve damage, and kidney damage could be reduced by taking statins.... 


High-salt Diet and High HBA1c May Increase Cardiovascular Disease

A synergistic effect may exist between HbA1c level and dietary sodium intake for the development of CVD.... 


Fibrates Can Reduce Cardiovascular Risk in Type 2's

This study showed that fenofibrate was very effective in lowering total, LDL, non-HDL cholesterol significantly in female diabetic patients compared to male patients.... 


LX4211 Improved Glucose Control without Dose-Increasing Glucosuria in Type 2 Diabetes

In patients with type 2 diabetes, LX4211 produced greater dose-ranging effects on HbA1c than on glucosuria.... 


Joslin's Diabetes Deskbook, Updated 2nd Ed., Excerpt #49: Pharmacotherapy of Type 2 Diabetes, Part 8

Richard S. Beaser, MD


Update: GLP-1 Analogs and Cardiovascular Health

David Joffe, BSPharm, CDE The cardiovascular morbidity and mortality associated with diabetes are well established, so much so that type 2 diabetes has been described as a cardiovascular...


Diabetes Clinical Case Series, Excerpt #8, Endocrinology and Diabetes

Oliver, aged 46, is found to have...


Diabetes Clinical Case Series, Excerpt #6, Endocrinology and Diabetes

Ramzi Ajjan, MRCP, Med Sci, PhD


Dissecting Dietary Determinants of Atherogenic Dyslipidemia and Targeting the Culprit Particles

Joy Pape, RN, BSN, CDE, WOCN, CFCN, FAADE Dr. Ronald Krauss, MD, Senior Scientist and Director of Atherosclerosis Research at...


Joslin's Diabetes Deskbook, Updated 2nd Edition, Excerpt #32: Macrovascular Complications, Part 4

Richard S. Beaser, MD Michael Johnstone, MD


Joslin's Diabetes Deskbook, Updated 2nd Edition, Excerpt #31: Macrovascular Complications, Part 3

Richard S. Beaser, MD Michael Johnstone, MD


Joslin's Diabetes Deskbook, Updated 2nd Edition, Excerpt #30: Macrovascular Complications, Part 2

Richard S. Beaser, MD Michael Johnstone, MD


Top Ten Things to Know: 2011 Effectiveness-Based Guidelines for the Prevention of CVD in Women

  In 2007, CVD caused about 1 death per minute among women in the US.


Top 10 Sodium Overkill Culprits (Patient Handout)

  Nine out of 10 Americans consume more sodium than they need, according to a new report...


Why Heart Rate Variability Is Key to Longevity and Healthy Aging

 


SPECIAL FEATURE: GLP-1 Agonist-based Therapies: An Emerging New Class of Antidiabetic Drug With Potential Cardioprotective Effects

Melanie Sulistio, MD, Curtis Carothers, MD, Mandeep Mange, BS, Mike Lujan, BS, Rene Ofiveros, MD, and Robert Chilton, DO PART 2: GLP 1 Agonist-based Therapies: How do they reduce...


United States of Diabetes Report

  You can use the information in this report to provide evidence for your ...


Psychology in Diabetes Care, 2nd. Ed, Part 9

Edited by Frank J. Snoek and T. Chas Skinner Diabetes in Adolescents


Managing Clinical Problems in Diabetes, Case Study #9: Mrs. MS

Edited by Trisha Dunning AM, RN, MEd, PhD, CDE, FRCNA and Glenn Ward MBBS, BSc, DPhil (Oxon), FRACP, FRCPath


Body Fat Calculator

  People ...


PRADAXA (DABAGATRAN), A New Anticoagulant for Stroke and Embolism Prevention

By Jennifer Freidman 2011 Doctor of Pharmacy Candidate, University of Florida Atrial fibrillation currently affects about 2.2 million Americans. If left untreated it can cause embolism ...


Diagnosis and Management of Type 2 Diabetes, 10th Edition, Ch 15, Pt2

Long-Term Complications and Treatments: Dyslipidemia


New Product: How high is your blood pressure? Ask your iPhone‎

How high is your blood pressure? Ask your iPhone‎ iHealth Lab has announced the iHealth...


A Year of Diabetes Research 2010

Prevention, therapy and complications are the keystones for diabetes research. It would be impossible to cover all of the developments in just one feature. So here is a brief summary of some of the best for 2010.


Editor's Note: Diabetes and Cardiovascular Disease, Lifestyle Habit Changes, and More....

Every week there is a new study coming out showing the relationship between diabetes and cardiovascular disease. There are over 1.1 million Americans who will have a serious heart attack in 2011 and there are over 80 million who have one or more...


Hyperglycemic Emergencies

Lana Kravarusic Doctor of Pharmacy Candidate, University of Florida 


Letter from the Editor, August 29, 2010: Popeye vs Wimpy

It appears there is a classic battle brewing between Popeye and Wimpy as to what works better for your health.  Popeye thinks he was right when he said, "I'm strong to the finich, 'Cause I eats me spinach," as a new study of over 220,000...


Heart Risk from Actos® as Great as from Avandia®, Study Suggests

According to a study published in Circulation: Cardiovascular Quality and Outcomes, the heart risk from Actos is just as great as the risk posed by Avandia according to a story published Tuesday, August 24 by the Los Angeles...


Essential Oils for the Management of Type 2 Diabetes

Ivory A. Gordon, Pharm.D....


America's Silent Killer: Oprah and Dr. Oz Want to Save Your Life

By...


Preventing Medication Errors

Institute for Safe Medication Practices


The Glucose – CVD Connection: The Search For The Missing Link

There is a new study out trying to show the link between intensive glycemic control and reductions, if any, in cardiovascular endpoints. The VA Diabetes Trial of 1,800 patients, showed like other, larger trials recently published, that there was no...


The Message for World Kidney Day 2009:

Hypertension And Kidney Disease: A Marriage That Should Be Prevented is the message for WORLD KIDNEY DAY 2009 and we have a special feature written jointly by Eberhard Ritz representing the International Society of Nephrology (ISN) and George...


HIV-infected patients are at an increased risk for developing Diabetes

More and more patients with HIV are controlling their disease well. When viral loads are under control, patients often are seen by clinicians for other problems. Diabetes seems to be one of those problems that get a lot of attention. My current...


Risks for Drug Induced Pancreatitis

With all the press lately about the incretin mimetics and pancreatitis our current intern, Jennifer Webb, PharmD Candidate, FAMU has taken a look at the facts, and compared the chances of pancreatitis among classes of drugs and how the risk of...


Charcot Foot: A Potenial Risk Factor for Diabetic Patients

Charcot Foot: A Potential Risk Factor for Diabetic Patients, is a valuable report on an under diagnosed problem written by Jennifer Webb, Doctor of Pharmacy Candidate, FAMU. You may want to print this out and hand it to your patients.


Presentations

Diabetes Mellitus 101 for Cardiologists, Part 16

In this week's Homerun Slides from Dr. Stanley Schwartz, we look into exactly what a more aggressive...


Diabetes Mellitus 101 for Cardiologists, Part 15

In this week's Homerun Slides, we continue our exploration of the positive effects of Ranolazine,...


Diabetes Mellitus 101 for Cardiologists, Part 14

In this week's Homerun Slides, we focus in on the specifics of the drug, Ranolazine, which is...


Diabetes Mellitus 101 for Cardiologists, Part 13

In this week's Homerun Slides, we review the positives and negatives of sulfonylureas, comparing them...


Diabetes Mellitus 101 for Cardiologists, Part 11

In this week's Homerun Slides, we cover the importance of the Incretin Effect with an examination of...


Diabetes Mellitus 101 for Cardiologists, Part 10

In this week's Homerun Slides, we continue with our review of diabetes therapy from a cardiovascular...


Diabetes Mellitus 101 for Cardiologists, Part 9

In this week's Homerun Slides, Dr. Stanley Schwartz continues his review of pioglitazone as a...


Diabetes Mellitus 101 for Cardiologists, Part 8

In this week's Homerun Slides, Dr. Stanley Schwartz reviews pioglitazone as a therapy for both...


Diabetes Mellitus 101 for Cardiologists, Part 7

 In this week's Homerun Slides, Dr. Stanley Schwartz discusses the "Adipocytokine...


Diabetes Mellitus 101 for Cardiologists, Part 5

  In this week's Homerun Slides, Dr. Stanley Schwartz talks about the Natural History of Type 2...


Diabetes Mellitus 101 for Cardiologists, Part 4

  In this week's Homerun Slides, Dr. Stanley Schwartz tackles the topic of the best blood glucose levels...


Diabetes Mellitus 101 for Cardiologists, Part 3

In this week's Homerun Slides, courtesy Dr. Stanley Schwartz, we delve deeper into the possible...


Diabetes Mellitus 101 for Cardiologists, Part 2

   In this week's Homerun Slides, courtesy Dr. Stanley Schwartz, we continue our examination of...


Diabetes Mellitus 101 for Cardiologists, Part 1

  In this week's slides series, courtesy Dr. Stanley Schwartz, we review some of the basics of diabetes mellitus...


Therapy of Type 2 Diabetes Mellitus, Update, Part 2

  In this week's set of Homerun Slides from Dr. Stanley Schwartz, we delve into the current state...


Quality Measures In Cholesterol and Diabetes Management, Part 1 of 4

  This week we have the first set of slides in a three-part series examining current treatment practices...


Hypertension in the Medicare Population, Part 2 of 2

In this second set of Homerun Slides on Hypertension in the Medicare Population, we review some...


Hypertension in the Medicare Population, Part 1 of 2

  In this week's Homerun Slides set, we take a look at the challenges posed by an increasingly...


Achieving Glycemic Control in the Hospital Setting, Part 3 of 4

In this week's set of Homerun Slides, our topics include IV Insulin Protocols, Considerations when...


Diabetes Mellitus 101 for Medical Professionals, Part 5 of 9

In this week's Homerun Slides, we cover such topics as the Potential Mechanisms of...


Diabetes Mellitus 101 for Medical Professionals, Part 2 of 9

In this week's set of Homerun Slides,...


Sleep Apnea

If your diabetes patients have sleep apnea, they may also have hypertension....


Diabetes Microvascular Complications, Part 1 of 2

Diabetes mellitus can lead to many acute and chronic complications. The chronic...


Understanding Acute Coronary Syndrome

Over twelve and half million Americans currently have heart disease and 1.1 million...


Insulin Resistance, Part 2 of 3: Inflammation Markers

Plasminogen is an acute phase protein and precursor to plasmin, which...



Cast Your Vote
Which type of incretin do you prescribe more?
CME/CE of the Week
John Steinberg, DPM

Category: General Diabetes
Credits: .75


Advertisement


Search Articles On Diabetes In Control