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Tag Archives: GLP-1 tolerance

GLP-1s and Gastric Motility Over Time: Does the Body Adapt?

Medical illustration showing GLP-1 therapy affecting gastric motility and stomach emptying in diabetes treatment

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have transformed the management of type 2 diabetes and obesity. However, one question clinicians increasingly ask is whether gastric motility adapts during long-term GLP-1 therapy. These medications slow gastric emptying, which contributes to appetite control and postprandial glucose reduction. Yet the human body often …

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