Tag Archives: advanced glycation end products

Diabetes care has advanced dramatically over the past decade. While therapies such as GLP-1 receptor agonists and SGLT2 inhibitors have transformed glucose management and cardiovascular outcomes, many patients continue to develop long-term complications. Could an older therapeutic target finally provide the missing piece? Interest in aldose reductase inhibitors for diabetes …

Most people think diabetes-related blood vessel damage begins only after years of high blood sugar. However, scientists are uncovering evidence that injury may start much earlier, in a structure so thin it cannot be seen during a routine medical exam. This microscopic layer, known as the endothelial glycocalyx, acts as …