Pediatrics

Type 1 diabetes in children and youth is typically characterized by weight loss, polyuria, polydipsia, blurring of vision, very high plasma glucose concentrations, and ketonuria.

‘Brittle’ diabetes is a controversial and fortunately uncommon disorder, described especially in the UK and USA, usually occurring in young women, with onset at puberty, and defined as a patient whose life is ‘constantly disrupted by episodes of hypo- or hyperglycemia, whatever their cause.’

Normal weight, physically active children thought to have higher executive function.

Higher glucose levels associated with odds of tetralogy of Fallot and serum glucose.

Severity of obesity associated with higher value of low HDL cholesterol level, high blood pressure and hemoglobin A1C levels.

Benefits seen after nine days despite lack of weight loss.

Depressive symptoms are more common than diagnoses and treatment.

Improvements seen in children with developmental delays associated with neonatal diabetes.

Higher doses of medication may lead to a mean increase of approximately 1 cm height.

Findings suggest that Metformin may help overcome pubertal insulin resistance and aid in better glycemic control.