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To understand NO metabolism in diabetic patients we must first discuss the normal process of NO formation. NO is a gas that is also a short-lived, unstable free radical and, within seconds of production, must become stabilized. To do so, it reacts with one or more elements or biologic compounds, as …

Nitric Oxide Synthase (NOS) is the enzyme that generates NO from L-arginine as described in Part 1 of this series. However, the enzyme exists in three different forms called isoforms. Each isoform synthesizes NO but does so under different conditions. Often all three isoforms will be found in the same …

This is the first in a series of articles that relate specifically to nitric oxide (NO), a free radical gas that is a powerful regulator of circulation (It is an endogenous vasodilator.) and a neurotransmitter (It helps in the processing of nerve signals as they cross synapses.). L-arginine, one of …

Diabetic patients with poor control of blood glucose face an increased risk of post-surgical complications and death following total hip or knee arthroplasty, according to a new study.

Sodium bicarbonate supplementation significantly slowed loss of kidney function and improved nutrition status in patients with advanced chronic kidney disease, data from a two-year study showed.

Major depression doubles the risk of incident diabetic foot ulcers, according to the results of a large, prospective, population-based cohort study…… 

Diabetics undergoing total joint replacement often are at a higher risk of experiencing complications after surgery due to various pre-existing health conditions, but those complications are less likely to occur when a diabetic patient has glucose levels under control.

Patients who underwent laparoscopic adjustable gastric banding achieved less weight loss and less improvement in comorbid conditions than those who had gastric bypass or sleeve gastrectomy.

Forty-six percent of patients over age 60 currently on the waiting list for a kidney transplant will die before they receive an organ from a deceased donor, reports an upcoming study.

Dr. Aaron Vinik, principle investigator for the study at Eastern Virginia Medical School in Norfolk, is testing a new diabetes drug, Prochymal.  It’s part of a first-of-its-kind study for finding a possible cure.