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Specialties

SPECIALTIES

Cyrus Desouza, MBBS, Q1: Cardiovascular Benefits of SGLT2s, GLP-1s, and DPP-4s?

Dr. Cyrus Desouza, MBBS, talks about the cardiovascular side effects of newer classes of drugs. SGLT2 inhibitors are still relatively new so there is not much information but they do show some weight loss effects, seem to lower blood pressure, and may have some CV benefits. However, we don’t know what they …

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Diabetic Emergencies: Diabetic Ketoacidosis in Childhood and Adolescence, Part 3 of 3

Diabetic_Emergencies

Christina Kanaka-Gantenbein, MD, PhD Acidosis management  Severe acidosis is reversible by fluid and insulin replacement. Insulin stops lipolysis and further ketone production and allows ketoacids to be metabolized, generating bicarbonate.4 Moreover, treatment of hypovolemia improves tissue perfusion and renal function, thereby increasing the excretion of organic acids. Controlled trials have …

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