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Lower IGF-1 concentration associated with higher fracture risk...

Postmenopausal women with normal glucose tolerance focus of study.

Screenings for diabetic retinopathy should begin at age 15 or 5 years after diagnosis....

Short periods of intense physical activity can improve heart structure and diabetes control...

Active smoking is associated with significantly increased risks of total mortality and cardiovascular events...

T2 patients may be at increased risk of developing tangles in the brain that indicate dementia.

Studies in heart failure and hypertension have shown that people who identify themselves as black may have a less active renin-angiotensin system and a lower bioavailability of nitric oxide. The A-HeFT study was conducted to determine if a fixed dose of isosorbide dinitrate (ISDN) and hydralazine would provide additional benefit in black patients with heart failure.

Thiazolidinediones (TZDs), rosiglitazone and pioglitazone, have been shown to increase fracture risk in women after a year of TZD use; however, there has been little data available on the effects of the discontinuation of TZD. This longitudinal observational cohort study used data from an ancillary study of skeletal health within …

Mineralocorticoid receptor antagonists (MRAs) are often used with a renin-angiotensin system (RAS) blocker to further reduce proteinuria in patients with CKD. However, eplerenone and spironolactone increase the risk of hyperkalemia in these patients. Finerenone (BAY94-8862) is a new nonsteroidal MRA that has better receptor selectivity than spironolactone, associating with lower …

Bone mineral density at hip and lower spine may also decrease.