Letter from the Editor
Most times when the FDA calls for an early discontinuation of a drug study, it is because there are complications, or the drug does not work at all. It is not often that good results cause an early discontinuation. This week our new intern, Marian Ayad, BPharm, PharmD candidate, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, has a special report on a drug that worked so well that the FDA called the study off early, and the ADA actually changed their guidelines because of the results. Click here to find out what drug and what the ADA changed.
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We can make a difference!
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Dave Joffe
Editor-in-chief
TOP STORIES -- Diabetes News and Research
Strong results motivate the ADA to update its Standard of Care for patients with diabetes.
The anti-inflammatory drug Hydroxychloroquine shows promise in off label use.
Devices like pumps, CGMs and automated insulin delivery systems should be used as manufacturers intended.
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Did You Know: Using Bedtime to Prevent Diabetes in Children and Adults
With childhood obesity rates high, many studies have investigated lifestyle factors that can make a difference: which ones increase the risk and which ones reduce it. A study published in The Journal of Pediatrics revealed that 4-year-old children who slept before 8 p.m. had a 50% lower obesity risk compared with those who slept after 9 p.m. Findings were based on about 1,000 children who were followed from birth to age 15. Beyond diet, a lack of sleep has been linked to weight gain in both adults and children, so it’s important that kids get enough sleep. As for most children, getting up time is usually determined by when school or day care starts and can’t be easily altered, an earlier bedtime is needed to ensure kids get the sleep they need. The researchers found that attention to sleep needs to start in the preschool years. For instance, 4-year-olds who went to sleep before 8 p.m. cut their obesity risk in half compared to those who went to sleep after 9 p.m. This simple lifestyle modification can make a lifelong health difference. What about enough sleep for adults? In the Nurses’ Health Study, researchers followed roughly 60,000 women for 16 years, asking them about their weight, sleep habits, diet, and other aspects of their lifestyle. At the start of the study, all of the women were healthy, and none had obesity; 16 years later, women who slept 5 hours or less per night had a 15 percent higher risk of developing obesity, compared to women who slept 7 hours per night. Short sleepers also had 30 percent higher risk of gaining 30 pounds over the course of the study, compared to women who got 7 hours of sleep per night.
Harvard School of Public Health
PatelSR, Malhotra A, White DP, Gottlieb DJ, Hu FB. Association between reduced sleep and weight gain in women. Am J Epidemiol.2006; 164:947-54.
Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:
Marian Ayad, BPharm, PharmD candidate, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences
Adam Chalela, B.S., Doctor of Pharmacy Candidate, Class of 2020, USF College of Pharmacy
Emma Kammerer, PharmD Candidate, Class of 2020, L|E|C|O|M Bradenton School of Pharmacy
Maya Rudolph, PharmD Candidate, Florida A&M University College of Pharmacy & Pharmaceutical Sciences
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