July 29, 2017 : Issue #896

• Beta Blockers And the Risk of CV Events in Type 2 Diabetes
• CDC: 100 Million Have Diabetes or Prediabetes
• Lipid-Lowering Effect of Extra Virgin Olive Oil and Atorvastatin in Type 2 Diabetes
• Estimating Concentrations of Chromium and Manganese in Diabetes Patients
• Link Between Serum Bilirubin and Diabetic Retinopathy in Type 2 Diabetes Patients
• Current Interview: Amin Zayani on MedAngel ONE Insulin Temperature Monitor

Over the years, there has been a lot of publicity and press on the benefits of chromium. It has been touted for weight loss, curing diabetes, lowering cholesterol, and improving testosterone levels. It seems that every few years a new “formula” appears that guarantees results, and many patients have had improvements using chromium. Now we have some concrete evidence that chromium, along with manganese, do make a difference for our diabetes patients and that these patients are more likely to have a deficiency. Our Doctor of Pharmacy candidate from LECOM College of Pharmacy, Nuha Awad, put the information together in our item # 4.

After you finish that article, why don’t you show off your prandial insulin brain power by trying your hand at this week’s Test Your Knowledge quiz?

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We can make a difference!

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Dave Joffe

Editor-in-chief

With the tentative approval, LUSDUNA Nexvue (insulin glargine injection), a follow-on biologic basal insulin, has met all required regulatory standards, but is subject to an automatic stay for 30 months due to a lawsuit from Sanofi for patent infringement, unless they win the court battle.

What percent of your patients with diabetes fail to meet national treatment targets for glycemic, blood pressure, or cholesterol control?
a) >50%
b) >75%
c) < 50% d) 25% Follow the link to see how you and your colleagues compare.

After 100 plus years, there is finally have a way with new technology to protect our insulin from temperature changes that can affect your health. MedAngel ONE is the best solution to monitor and protect temperature sensitive medications like insulin. Continuous monitoring and logging ensures that you and your patients can always see beyond doubt if medications were stored properly. It supports hundreds of FDA-approved medications and adapts the smart alerts to them. If a dangerous temperature is approached or exceeded, the app will alert you immediately. Learn more about MedAngel from the inventor, Amin Zayani.

MedAngel ONE is available at Doctor’s Option. For a special discount + Free shipping Use code: Med10.

Amin Zayani is the founder and CEO of MedAngel. He works with his team of engineers, pharmacists and designers on improving drugs safety for patients who live with diabetes and rely on temperature sensitive drugs like insulin. Their solution, MedAngel ONE brings a simple and easy to use temperature monitor that is compatible with smartphones and supports all FDA-approved insulins and many more medications.

Your patient has been systematically titrating his basal insulin dose for the last 6 months; his daily dose is NPH .90 U/kg/day. Despite his good efforts, you decide it would be prudent to add a prandial insulin dose to his treatment regimen. Which of the following scenarios might lead you to this conclusion?

A) A1C=7.4%, FPG<130 mg/dl, PPG>180 mg/dl
B) A1C=7.0%, FPG<130 mg/dl, PPG<180 mg/dl C) A1C=7.0%, FPG<120mg/dl, PPG<160mg/dl D) A1C=6.8%, FPG<120 mg/dl, PPG<160 mg/dl Follow the link to see if you got it right.

The U.S. Department of Agriculture conducted a study that suggests that adding a sugary drink to a high-protein meal decreases the effectiveness of the body’s fat-burning mechanism by about 8 percent. In addition, this combination of foods and beverages also increases cravings for savory and salty foods afterward. As earlier studies indicated that high-protein meals increase the body’s ability to burn fat, the researchers were surprised by the outcome that it appears that adding sugary beverages produce the opposite effect.  The study involved 27 healthy adults who were given specific meals in isolated rooms over two 24-hour periods. Researchers calculated how the foods affected metabolism, including how the participants burned calories and broke down fat, protein, and carbohydrates. Sugar-sweetened beverages decreased fat-burning ability and did not cause the participants to feel fuller. The study results were published in BMC Nutrition.

Beta-blocker use in patients with T2DM and established CV risk factors associated with increased risk of CV events and severe hypoglycemia, according to recent study.

The growth of diabetes in the United States may be slowing, but it is still increasing. Just how bad can it get?

Extra virgin olive oil, like statins, promotes lipid lowering in people with diabetes who have dyslipidemia.

Serum concentration levels of both chromium and manganese metals are altered in people with and without diabetes.

Serum bilirubin is inversely correlated with diabetic retinopathy predicting progression of retinopathy over time.

Quote of the Week!

“Man needs difficulties; they are necessary for health.”

…Carl Jung

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletter:

Nuha Awad, Doctor of Pharmacy Candidate: Class of 2018; LECOM College of Pharmacy

Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
810 Bear Tavern Road Suite 102
Ewing, NJ, 08628
USA
www.diabetesincontrol.com