November 19, 2016 : Issue #860

• Renal Outcomes With DPP-4 Inhibitors, SGLT-2s, and GLP-1 Agonists
• Losing Weight Increases Hunger
• Belly Fat Risk for CVD Worse than We Thought
• Can Statins Offset Insulin-Related Cancer Risk in T2DM?
• Incidence of Diabetes with Statin Use
• Exclusive Interview: Jeffrey Dachis, Founder and CEO of One Drop
  Transcript  |  Video

Recently I got to spend some time with the director of a kidney / liver transplant center in Largo, Fl. While I was touring the facility she was telling me about how they select candidates for kidney transplant, and the problems that keep people from being selected. We also talked about the time they spend on dialysis, and how many people never get the transplant because there are not enough donor organs to go around. After listening to her describe the heartbreak that families feel when they are told they haven’t qualified, I realized that we need to do a better job of keeping our diabetes patients from needing a kidney to begin with. One way we can do this is to make sure we are using drugs to treat their diabetes that have a positive effect. This week our first item looks at which drugs can deliver a positive effect.

Another way we can help save those kidneys is by closely monitoring factors that affect glucose readings, and this week Steve Freed sits down with Jeffrey Dachis to discuss the possibilities of using One Drop Mobile to to accomplish that.

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We can make a difference!

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Dave Joffe, Editor-in-chief

Which treatment do you feel most comfortable with for type 2 patients?
1. DPP-4
2. GLP-1
3. SGLT-2
4. Sulfonylurea
5. TZD
6. Insulin
Follow the link to share your opinion and see what your colleagues think!

One Drop Mobile is an award-winning diabetes management solution delivered entirely via mobile app. Since launch, One Drop Mobile users from over 190 countries worldwide have logged over 1,500,000 user sessions. One Drop Mobile provides real-time and historical blood glucose data and analytics to empower people with diabetes and their healthcare providers to see relationships between health behaviors and health outcomes. The app highlights blood glucose patterns, providing support for behavior change and, if necessary, medication adjustments. One Drop Mobile’s interface also makes it easy for users to share health information. “By bringing diabetes technology up to speed with the rest of our lives, we are making health data accessible and actionable, and empowering everyone using One Drop to make better decisions, together,” said Jeff Dachis, founder and type 1 and CEO of One Drop. See our interview with Jeff Dachis, item 6 below.

You are seeing a 57-year-old man whose 10-year cardiovascular risk profile suggests that he should receive a low-dose statin. What should you consider regarding statins and the risk for incident diabetes?

a. Statins are not associated with any significant difference in the risk for diabetes.
b. Statins can increase the risk for incident diabetes by 48%.
c. Statins may particularly promote diabetes among older adults.
d. A total of 255 patients receiving statins for 4 years would produce 1 additional case of diabetes.

Did you get it right? Follow the link to find out!

In a recent industry-funded study, published in the Annals of Internal Medicine, researchers analyzed 60 studies published from January 2001 to July 2016 and found that 26 out of 26 papers that didn’t find an association between diabetes or obesity and sugar-sweetened beverages, such as soda and fruit drinks, were industry-funded, compared with one industry-funded paper in another 34 studies that found a link. So if you ask the question, can sugar-sweetened drinks be tied to obesity and diabetes, you should probably look at who funded the study. “The industry seems to be manipulating contemporary scientific processes to create controversy and advance their business interests at the expense of the public’s health,” the researchers write.  To see the other side of the issue, you can check out this fact sheet from the Department of Nutrition at Harvard School of Public Health. Harvard Fact Sheet (pdf)

Data from 2 trials show long-term use can improve albumin/creatinine ratio, but not other renal outcomes.

New study finds that when you lose weight, you will consume more calories than necessary to maintain the lower weight.

One type of belly fat may be more risky, according to results from an imaging-based study.

Greater risk reduction in those not receiving antihyperglycemic treatment.

Diabetes increased modestly in general.

Jeffrey Dachis discusses how his own experience with type one diabetes led him to develop the One Drop diabetes app to help other people with diabetes improve self-care.

Jeffrey Dachis and Diabetes in Control Publisher Steve Freed discuss the new app that compiles the various sources of diabetes information into one place for the purpose of better self-management and improved self-care.

Quote of the Week!

“Diets, like clothes, should be tailored to you.”

…Joan Rivers

Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
810 Bear Tavern Road Suite 102
Ewing, NJ, 08628
USA
www.diabetesincontrol.com