July 11, 2020 : Issue #1050

TOP STORIES — Diabetes News and Research

Correlation Between T2DM and Cancer Risk

Gastric Bypass Surgery in Patients with Type 2 Diabetes

Consumption of Certain Macronutrients at Dinner Could Affect Mortality

The CDC just released new coronavirus risk guidelines and there has been a change. Now if you have type 2 diabetes you are at an increased risk, but if you have type 1, you only may be at increased risk. This small change means that your chances of a negative outcome if you contract the coronavirus are increased if you have type 2 (see attached chart for the latest update).

If this is not enough to worry about, our intern Leyany Feijoo Ramos, PharmD. Candidate, LECOM School of Pharmacy, has found a couple of studies that show if you have type 2 you are at a much higher risk of Pancreatic, Kidney and Uterine cancer.

Just a few more reasons to keep that A1c around 6.

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We can make a difference!

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Dave Joffe

Editor-in-chief

• Metformin Hydrochloride Extended-Release Tablets USP, 500 mg and 1000 mg by Lupin Pharmaceuticals: Recall – Due to the Detection of N-Nitrosodimethylamine — Read Recall
• Metformin Hydrochloride Extended-Release Tablets USP 750 mg by Granules Pharmaceuticals: Recall – Due to the Detection of N-Nitrosodimethylamine — Read Recall

Our updated 2020 Insulin Chart allows you to easily compare different brands of insulin across a range of factors including form, onset, duration, and cost.

Download Insulin Chart (PDF format)

A recent study suggests strengthening cancer screening recommendations may be beneficial in patients with T2DM.

What are the pros and cons of bariatric surgery, and how do results affect renal and cardiovascular outcomes?

A recent study evaluated the impact of macronutrient distribution throughout the day on mortality risk in patients with diabetes.

A new study published in The Journal of Physiology has revealed that 12 weeks of passive stretching — in which you remain in one position, and a partner, accessory or prop stretches your muscles through external pressure — can help improve blood circulation in the body by decreasing the stiffness of the arteries and helping them dilate. The study indicates that the improvements observed in the blood flow of the subjects due to easy-to-administer passive stretches can also reduce the risks of diseases related to the vascular system, namely stroke, heart disease, hypertension, and diabetes.

Researchers at the University of Milan assigned 39 healthy participants of both sexes to two groups. The control group didn’t undergo any stretching. The experimental group performed leg stretches five times a week for 12 weeks. Researchers evaluated the effect of passive stretching on the blood flow locally and in the upper arm. They found that the arteries in both the lower leg and upper arm had increased blood flow and dilation when stimulated, along with decreased stiffness. Both of these changes may have implications for diseases such as heart disease, stroke, and diabetes as they are characterized by changes in blood flow control, due to an impaired vascular system. If this study is replicated in patients with vascular disease, it could indicate whether or not this training method could serve as a new drug-free treatment for improving vascular health and reducing disease risk, especially in people with lower mobility.

After passive stretching training, vascular function and arterial remodeling improved, and arterial stiffness decreased in all the arteries, suggesting modifications of both central and local blood flow control mechanisms. Passive stretching‐induced improvements related to central mechanisms seemed to have a short duration, as they returned to pre‐training baseline within six weeks from training cessation. In contrast, those more related to a local mechanism persisted in the follow‐up.

Examples of passive stretching exercise (PDF format) 

The Journal of Physiology  July 1, 2020; The Journal of Physiology April 1, 2018 

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:

Stephanie Anderson, PharmD Candidate 2021, Skaggs School of Pharmacy and Pharmaceutical Sciences  

David Clarke, PharmD Candidate, University of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences

Kenya Henderson, 2021 PharmD. Candidate, Florida Agricultural & Mechanical University, College of Pharmacy and Pharmaceutical Sciences

Leyany Feijoo Ramos, PharmD. Candidate, LECOM School of Pharmacy

Sandra Zaki, PharmD Candidate, Florida A&M University

Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
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