TOP STORIES — Diabetes News and Research
Trending High Fat and Protein Diets May Need Insulin Dose Adjustments
Letter from the Editor
A couple of weeks ago I shared some of the success my wife was having with the Control-IQ technology on her T-slim pump. Last week one of my former interns, who is a professor at Nova Southeastern College of Pharmacy, reached out to me to share her success as well.
Tandem, the maker of the T-slim pump and Control-IQ, is not just resting on their laurels and this week our intern Mit Suthar, PharmD. Candidate, LECOM College of Pharmacy, has a nice overview of what they have for our patients going forward.
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We can make a difference!
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Dave Joffe
Editor-in-chief
Newsflash: Senseonics Suspends New 90-Day Eversense Sales
Senseonics effectively ceased operations, per an 8-K filed on Thursday. The Company is, effective immediately, suspending commercial sales in the United States of its 90-day Eversense continuous glucose monitoring (“CGM”) system to new patients and physician practices. The company stated that it intends to continue distributing the 90-day Eversense system to patients currently using the system for the foreseeable future.
TOP STORIES — Diabetes News and Research
Which GLP-1RA provides better benefits?
Do meals with high fat or high protein content allow for the prescribed insulin dose to balance a patient with type 1 diabetes’s glucose levels?
A breakthrough in software for insulin pumps approved by the FDA.
Did You Know? New Study Shows That Gender Can Affect How We React to Fasting
Fasting may be beneficial for health, potentially reducing susceptibility to diseases, including diabetes and high blood pressure. But we don’t yet know which type is best and for whom. Fasts can vary in length and time of day, and this can also determine how easily people can stick to them. According to research published in The Journal of Physiology, in response to short, six-hour fasts in mice, female mice put on more liver fat than males, but also seemed to be better at using it up. Researchers at the University of Sydney fasted mice for six hours each night over four weeks. They chose the night because this is the active phase of the mice, mimicking daytime fasting in humans. In some aspects, males and females responded similarly to the short daily fasting, with both showing changes in food intake, lean mass, and glucose metabolism. However, these parameters changed to different extents, with males eating more, growing bigger, and having larger livers. The key difference between the sexes was found in the liver with fat storage and usage in the liver, differing in males and females.
After four weeks of short daily fasting, female mice had accumulated more liver fat compared to males, but also showed increased potential for using those stores – better at storing lipids, but even better at using them. This suggests fasting is may be more beneficial to women, specifically in terms of liver health, which impacts the likelihood of developing diabetes, high blood pressure, and kidney disease. However, more research is needed to find out whether this applies to humans. A significant finding from this study is that in preclinical studies, it is essential to include both sexes.
Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:
Antonio Bess, Pharm D Candidate, Florida Agricultural & Mechanical University School of Pharmacy
Mit Suthar, PharmD. Candidate, LECOM School of Pharmacy
Chardae Whitner PharmD Candidate L|E|C|O|M Bradenton School of Pharmacy
Alayna Marteal Wyre, Pharm. D. Candidate, South College School of Pharmacy
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