TOP STORIES — Diabetes News and Research
Stay Hydrated Without Overhydrating for Exercise
by Sheri Colberg, PhD
Letter from the Editor
We missed the hurricane here in Tampa Bay, but the temperature has really cranked up. This morning when we finished our 43 mile ride the temp had hit 91 degrees and the heat index was 106, and that was at 11 AM. When these conditions exist it is not unusual to lose 8-9 lbs. of water weight, even if you hydrate the whole ride. This fluid deficit can be bad for anyone, but if you have diabetes it can be devastating. This week our activity expert, Dr. Sheri Colberg, shares her information on how to best hydrate without overdoing it.
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We can make a difference!
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Dave Joffe
Editor-in-chief
TOP STORIES -- Diabetes News and Research
by Sheri R. Colberg, PhD
Adequate fluid intake is essential to living well at any age, and being dehydrated can impact your health and your athletic endeavors. While it is harder to stay hydrated when exercising in the heat, you can dehydrate under other conditions—even during exercise in cold temperatures if you wear lots of clothing and sweat underneath it. As people grow older, they also begin to lose some of their normal thirst sensations, thereby increasing the risk for dehydration unless they make a conscious effort to drink more.
How reliable are random plasma glucose levels (RPGs) compared to fasting blood glucose or A1c?
Brown adipose tissue may play a role in glucose metabolism, and thus influence the risk of developing diabetes.
Did You Know: Outcomes From 100,000 Patients on Low Carb Diets for Diabetes
The Prospective Urban Rural Epidemiology (PURE) observational cohort study included more than 100,000 individuals, aged 35-70 years old, from 18 countries. Participants were followed for an average of 7 years. The goal of PURE was to assess the association between fat and carbohydrate intake with non-cardiovascular mortality and overall mortality. Results indicated that high carbohydrate intake was linked to higher non-cardiovascular and overall mortality. These results support the carbohydrate-insulin model theory that suggest postprandial hyperinsulinemia not only has negative metabolic effects, but also plays a role in malignant growth. The PURE findings were so impressive that the authors suggested a revision of recommended carbohydrates in dietary guidelines to reflect a low carbohydrate diet. Since the PURE study is observational it cannot prove causality and indicates a need for further research.
Despite numerous studies proving the benefits of a low carbohydrate diet in diabetic patients, the latest recommendations do not support this diet. This is due to the discrepancies between various studies, heterogeneity of low carb diets, fear of a poor lipid profile, and lack of data on long term safety and efficacy. Despite the controversy, reducing carbohydrate intake appears to be a valid choice to improve diabetes outcomes, but is not appropriate in all patient populations. Due to ketosis, this diet plan is not recommended in patients who are pregnant or lactating, have eating disorders, or those with renal disease. Furthermore, patients taking SGLT-2 inhibitors should avoid low carbohydrate diets due to an increased risk of diabetic ketoacidosis with this drug.
Bolla, etal. “Low-Carb and Ketogenic Diets in Type 1 and Type 2 Diabetes.” Nutrients, vol. 11, no. 5, 2019, p. 962., doi:10.3390/nu11050962.
Brinkworth, Grant. “The Role of Very Low Carbohydrate Diets for Enhancing Type 2 Diabetes Management.” Journal of Diabetes & Metabolism, vol. 07, no. 06, 2016, doi:10.4172/2155-6156.c1.044.
Kassey James, Pharm.D. Candidate, LECOM School of Pharmacy
Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:
Keri Hames, PharmD Candidate, Florida A&M University, College of Pharmacy & Pharmaceutical Sciences
Kassey James, Pharm.D. Candidate, LECOM School of Pharmacy
Joel John, Pharm.D. Candidate, Florida A&M University, College of Pharmacy & Pharmaceutical Sciences
Emma Kammerer, L|E|C|O|M Bradenton School of Pharmacy, PharmD Candidate
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