November 28, 2017 : DCMS #373

DISASTERS AVERTED — Near Miss Case Studies

How Long Does the Insulin Last? Do The Math!

EXCLUSIVE INTERVIEW — Candid Video Interviews with Top Practitioners

Aaron Vinik Part 4, Cycloset

HOMERUN SLIDES — Great Clinical Presentation Highlights

Diabetes 2017 Part 3

CLINICAL GEMS — The Best from Diabetes Texts

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #101: Pathogenesis of Nonalcoholic Fatty Liver Disease (NAFLD) Part 3

MOST POPULAR ARTICLES OF THE MONTH

#1 1-Hour Post-Prandial Glucose Predicts Risk For Type 2 Diabetes
#2 Awareness of Type 3C Diabetes and Why It Is Misdiagnosed
#3 Type 1 Cured in Mice

Dr Aaron Vinik has worked with us for many years and I am continually fascinated by his forward thinking and the respect he garners from the top opinion leaders in diabetes.

Over the past 10 years, there have been researchers who seem to have a left-field idea that may just work, but they are often in the spotlight for a short time and then they and their ideas are forgotten. Dr. Vinik is not one of those.

His early research in the use of the INGAP protein started a thought process in diabetes that is still evolving. He was one of the early adapters of medications that improve cardiovascular health in diabetes patients. Steve caught up with him at the recent AACE convention in Austin, where he shared what he is doing to improve cardiovascular outcomes. Last week, he got started talking about diabetes drugs that improve cardiovascular outcomes and this week he spends some extra time on his favorite drug for those patients.

Dave Joffe

Editor-in-chief

In assessing an in-patient’s diabetic educational needs, I was reviewing with him his in-home regimen for his insulin therapy. Per his report, he stated that he took Levemir 50 units twice a day. I asked if it was by needle, syringe and vial preparation, which it was. I instructed him re: the shelf life of Levemir of 42 days once opened. He stated, “I throw it out after a month, but there is always insulin in the vial.” He also said he has more than an adequate supply. He was receiving his insulin by mail-order, receiving as he should, but not using it in a timely fashion. In other words, he was stockpiling his insulin.

In part 4 of this Exclusive Interview, Dr. Aaron Vinik talks with Diabetes in Control Publisher Steve Freed during the AACE 2017 convention in Austin, Texas about the untapped possibilities of Cycloset.

In this week’s Homerun Slides, FDA-approved GLP-1s and GLP-1s in development.

Cause of NAFLD: physical inactivity: Although physical training predominantly enhances muscle insulin sensitivity, cross-sectional epidemiologic data and studies on effects of physical training suggest that exercise may decrease liver fat even in the face of unchanged body weight [50]. In a cross-sectional study in 72,359 healthy Korean adults, subjects who were exercising regularly had a 28–53% lower risk of NAFLD across almost all BMI deciles.

Study finds diabetes complications and mortality may be better predicted with elevated 1-hour blood glucose levels compared with 2-hour blood glucose levels.

Diabetes has long been divided into type 1 and type 2. But a third type has entered the mix — and we aren’t diagnosing it correctly.

Ralph DeFronzo and his researchers at UT Health at San Antonio announced that they have cured type 1 diabetes.