September 13, 2016 : DCMS #310

DISASTERS AVERTED — Near Miss Case Studies

 CGM? Still Perform the Fingerstick!

EXCLUSIVE INTERVIEW — Candid Video Interviews with Top Practitioners

Dr. Stanley Schwartz Part 3, Using Evidence-Based Practice

HOMERUN SLIDES — Great Clinical Presentation Highlights

Team-Based Approaches to Help Older Adults with T2 Achieve Individualized Glycemic Goals Part 3

CLINICAL GEMS — The Best from Diabetes Texts

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #41: Normal Beta-cell Function Part 6 of 6

MOST POPULAR ARTICLES OF THE MONTH

#1 Metformin for Prediabetes: Success
#2 Blood-Pressure Drug Could Be A Possible Type 1 Diabetes Cure
#3 Early Short-term Intensive Insulin Causes the Remission of Type 2 Diabetes

Many publications take advantage of videos of Key Opinion Leaders in order to share information with their readers. Most of them will also convert the interview to a transcript. Most times a transcript is good when it is technical knowledge, but there are times when the information is more thought-provoking, or the passion and nuances of a speaker can never be recreated, in a transcript.

Dave Joffe

Editor-in-chief

College student, type 1 diabetes, wears a pump and CGM. She has good family support. Several of her family members get her CGM readings on their phone. She received a call from her mother about 2:45 am waking her up. She told her to treat her low blood glucose, which patient reported to be 41.

In part 3 of this Exclusive Interview about the new diabetes classification, facilitating the individual use of “evidence-based practice” to individually assess the situation of a specific patient, instead of allowing media supposition about a drug class — such as SGLT-2s — to dictate diabetes treatment.

In this week’s Homerun Slides, ADA guidelines and other special considerations in the treatment of older T2 patients.

Beta-Cell function and glucose homeostasis: Insulin secretion, together with the sensitivity to insulin of glucose-utilizing tissues, is a key player in glucose homeostasis. What is relevant for glucose homeostasis is not the absolute insulin secretion levels but insulin secretion relative to glucose, as typically assessed by the beta-cell dose-response during the physiologic condition of oral glucose ingestion. Thus, beta-cell glucose sensitivity is strongly inversely associated to mean glucose levels during a standard OGTT and explains, together with insulin sensitivity, a substantial proportion of the variability in glucose levels.

In a controlled trial, 600 overweight and obese people with prediabetes were given metformin.

A common blood pressure drug is showing new promise to help treat and cure type 1 diabetes.

Starting patients diagnosed within the last 7 years on 2-4 weeks of intensive insulin therapy could help keep them off additional medications for at least 48 weeks.