August 9, 2016 : DCMS #305

DISASTERS AVERTED — Near Miss Case Studies

Alternative Therapies for Type 1 Anger Me

EXCLUSIVE INTERVIEW — Candid Video Interviews with Top Practitioners

Kimberly Ward Part 4, The Accu-Chek System Difference

HOMERUN SLIDES — Great Clinical Presentation Highlights

Beta-Cell Classification of Diabetes and the Egregious Eleven Part 4

CLINICAL GEMS — The Best from Diabetes Texts

International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #36: Normal Beta-cell Function Part 1 of 6

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When a patient has a sudden and continued spike in glucose levels, we often look to check their insulin levels by ordering a C-Peptide test. We know that this test measures in vivo insulin based on the measurement of C-Peptide, which is co-secreted with insulin in equimolar amounts as a consequence of pro-insulin cleavage. However, there are many other factors that affect how in vivo insulin works that we often don’t look at. These factors may explain why our best efforts to manage a patient’s glucose fail.

This week our clinical text delves in to the multiple factors that we need to consider in order help these difficult patients succeed.

Dave Joffe
Editor-in-chief

I’ve been with many a person who has type 1, when the person is told if they would just eat, drink, or rub this potion on their body, or if they would just think a certain way, they would no longer have type 1 diabetes. When I see or hear this, I become very angry and protective. Today, a woman who has had type 1 diabetes for almost 30 years told me she went to an alternative healer for an essential oils treatment. The “healer” told her if she would rub the cinnamon oils on her ankles it would heal her diabetes. She asked me what I thought.

In part 4 of this Exclusive Interview, DIC Publisher Steve Freed asks how does the Roche system differ from other products currently on the market?

In this week’s Homerun Slides, the cardiovascular benefit of the newer diabetes algorithm and treatment process.

Insulin is an ancient hormone; it emerged early in evolution since the most primitive forms of vertebrates (extant lamprey and hagfish) evolving from insulin-like peptide genes, which are expressed in all multicellular animals. From an evolutionary point of view insulin facilitates survival in an environment where access to nutrients is discontinuous, erratic, and difficult, requiring the function of highly specialized tissues necessary to allow movement and appropriate reactions to external stimuli (i.e., skeletal muscle and nervous system). Insulin, in the fed state is secreted to stimulate glucose and amino acids uptake allowing the build-up of depots of glycogen, proteins and lipids, which are necessary to sustain the energy requirements during successive fasting.