October 27, 2015 : DCMS #264

DISASTERS AVERTED — Near Miss Case Studies

Insulin Storage Impacts Effectiveness

HOMERUN SLIDES — Great Clinical Presentation Highlights

The Present and Future of Insulin Therapy Part 13

CLINICAL GEMS — The Best from Diabetes Texts

Practical Diabetes Care, 3rd Ed., Excerpt #35: Lipids Part 6 of 6

EXCLUSIVE INTERVIEW — Candid Video Interviews with Top Practitioners

Martijn Verschoor – Team Novo Nordisk

MOST POPULAR ARTICLES OF THE MONTH

#1  Bacterial Link Between Heart Disease and Gum Disease Clarified
#2 Artificial Pancreas for Type 1 Diabetes
#3 FDA Approves New Long-Acting Insulin: Tresiba and Ryzodeg

This week the riders from Team NovoNordisk are competing in the Tour of Hainan. We have an exclusive interview with Dutch rider, Martijn Verschoor, regarding what he likes to eat before a race and how he maximizes his potential. Martijn’s regimen must be working because he has had 2 top 10 finishes in the UCI race. Check out his Exclusive Interview.

Have you ever put 2 cups of sugar and only one cup of flour in a bowl to make cookies? After you do all the mixing and put them in the oven, you find out that you read the recipe wrong and the cookies are no good. Well the same mess up of directions can occur with insulin in the most unbelievable ways. This week our diabetes disaster avoided looks at what happens when the box is in the wrong place — see if you can figure out what went wrong.

Announcements

The Drug Lookup tool is now live again on our web site! You can access it here or from anywhere on DiabetesInControl.com — just look for it on the right side of each page. Search by brand name, scientific name, or drug class.

Reminder – just a few more days left to enter the Diabetes In Control contest! We’d like to hear your best suggestions to help prevent insulin errors at home, at pharmacies, and in the hospital. The contestant who submits the winning idea will receive a $100 Amazon gift card! Click here for more information and to enter! You may submit as many entries as you wish. Deadline to enter is November 1^st.

Your partner in diabetes care,
Dave Joffe
Editor-in-chief

Recently a patient presented to our outpatient diabetes education center. His A1C had historically been elevated, despite the initiation of insulin therapy and increasing doses. The patient reported that he had taken all insulin doses as ordered, but was frustrated with his lack of progress….

In this week’s Homerun Slides, the results of a multinational, placebo-controlled, randomized, double-blind, parallel-group, 24-week study involving patients who were receiving insulin (not routine pre-meal short- or rapid-acting insulin, except as pre-mixed insulin) administered alone or in combination with metformin (³1500 mg per day) and who had inadequate glycemic control (A1C ³7.5% and ≤11%).

Plant sterols, hydrogenated to stanols, reduce cholesterol absorption. At the recommended intake of 2 g/day they can lower total cholesterol by 12–14% and LDL by 13–16% (e.g. 0.3 mmol/L, 12 mg/dL) in both type 1 and 2 patients.

With multiple Top 10 finishes, veteran Team Novo Nordisk rider Martijn Verschool is back in the saddle this week as he prepares to compete in the Tour of Hainan.

A bacterial species common to both diseases increases arterial inflammation by altering gene expression.

Closed-loop system at home over 12 weeks feasible in type 1 patients.

FDA approved new long-acting insulin degludec for treatments of diabetes mellitus.