Head-to-Head Comparison: Oral Semaglutide vs. Empagliflozin

Nov 23, 2019

Editor: Steve Freed, R.PH., CDE

Author: Jordan Boyd, PharmD. Candidate Florida Agricultural & Mechanical University School of Pharmacy

The first oral glucagon-like peptide receptor agonist recently gained FDA approval, but how does it compare to oral agents already on the market?

With the recent approval of the first oral glucagon-like peptide agonist, Rybelsus (semaglutide), many clinicians are wondering how it stacks up to oral agents that they may already be utilizing in practice. The PIONEER-2 trial conducted by the manufacturer of Rybelsus, Novo Nordisk, evaluated several outcomes associated with its new drug versus Jardiance (empagliflozin) in an open-label, head-to-head comparison....

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