Did You Know? A New Aspirin Formulation Easier on Stomach

A New Aspirin Formulation Easier on Stomach: The main contraindication for aspirin that prevents people from using it are ulcers and GI irritation. A recent clinical trial involving a new drug formulation incorporating aspirin with soy-derived phosphatidylcholine found that the drug combination significantly reduced irritation to the stomach and upper gastrointestinal tract. Healthy volunteers with an age-associated risk of ulceration who took the combination had 70% fewer gastrointestinal ulcers than those receiving regular aspirin. PL2200 previously has demonstrated equivalent antiplatelet activity, which suggested the product is the bioequivalent to regular aspirin in promoting heart health. Mechanistically, this formulation could provide an alternative to regular aspirin. American Journal of Gastroenterology-online, Jan 2011