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Brain Health And HbA1c In Prediabetes

Apr 20, 2021
 
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Macrina Ghali, PharmD Candidate 2021, Florida A&M University, College of Pharmacy and Pharmaceutical Sciences

Data analysis suggests that patients with prediabetes have a similar risk for declines in brain function to patients diagnosed with diabetes.

Hyperglycemic states have been associated with poor cognitive function, dementia, and brain alterations. However, no studies have been conducted to evaluate the impact of prediabetes on neurological function. A study conducted in the United Kingdom (UK) sought to assess the association between various glycemic states and their effect on Alzheimer's disease risk, vascular dementia risk, baseline cognitive function, cognitive decline, hippocampal volume, and white matter hyperintensity volume.

 

The study was pulled from the UK Biobank and included 449,973 patients from 40 - 69 years of age during 2006 - 2010....

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